Management of Atrial Fibrillation
This JAMA Clinical Guidelines Synopsis summarizes the 2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation.
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Diagnosis and Treatment of Polycythemia – A Review
Importance Polycythemia vera (PV), a myeloproliferative neoplasm characterized by an increased red blood cell mass and increased risk of thrombosis, affects approximately 65 000 people in the US, with an annual incidence of 0.5 to 4.0 cases per 100 000 persons. Observations Erythrocytosis (hemoglobin…
Communication About Harm Reduction With Patients Who Have Opioid Use Disorder
This JAMA Insights explores how clinicians can use the harm reduction communication framework to engage with patients who have opioid use disorder, which could help prevent overdose and other substance use related harms.
Harm Reduction Strategies for People Who Use Drugs
This JAMA Insights explores harm reduction strategies for people who use drugs and the clinicians who treat them to help reduce the risk of unintentional drug overdose and infection.
Improving Patient Comprehension Through Explanatory Communication
This JAMA Insights illustrates how explanatory communication strategies can help improve patient comprehension, including adherence to treatment recommendations and self-management.
Differential Legal Protections for Biologics vs Small-Molecule Drugs in the US
Importance Biologics approved by the US Food and Drug Administration (FDA) receive 12 years of guaranteed protection from biosimilar competition compared with 5 years of protection from generic competition for new small-molecule drugs. Under the 2022 Inflation Reduction Act, biologics are…
Dengue
This JAMA Insights explores several aspects of dengue virus infection, including epidemiology, diagnosis, and clinical management, following a global resurgence in both endemic and nonendemic regions.
Antiretroviral Drugs for Treatment and Prevention of HIV in Adults: 2024 Recommendations of the International Antiviral Society–USA Panel
Importance New data and new antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection. Objective To provide updated recommendations for HIV treatment and clinical management and HIV prevention. Methods A panel of volunteer expert physician scientists…
Axial Spondyloarthritis – A Review
Importance Axial spondyloarthritis is an immune-mediated inflammatory condition involving the sacroiliac joints, spine, and peripheral joints. It affects approximately 1% of adults in the US and is associated with impaired physical function and reduced quality of life. Observations Inflammatory chronic back pain…
Allogeneic Stem Cell Donation
This JAMA Insights discusses allogenic stem cell donation, including the donation process and the effects of stem cell donation on donors.
