Diagnosis and Treatment of Patients With Primary Aldosteronism
This JAMA Insights discusses various aspects of primary aldosteronism, such as its epidemiology, diagnosis and screening, and treatment, including effective medication management.
JAMA
Vaccines for Cancer – A Translational Science Review
Importance Advances in tumor immunology and vaccine technology are reshaping cancer vaccine development after decades of limited clinical success. More than 2000 immunogenic tumor proteins or antigens have been identified, the types of immune responses required for tumor eradication have…
Medicolegal Evaluations for Asylum Seekers
This JAMA Insights discusses the importance of medicolegal evaluations for those seeking asylum and encourages clinicians to complete additional training to conduct these evaluations.
Patents on Small-Molecule Drugs Approved by the US Food and Drug Administration, 1990-2019
Importance Patent protection allows pharmaceutical companies to charge high prices for prescription drugs during periods of market exclusivity, and their expiration usually defines when generic competitors can enter the US market. Patents on drug active ingredients are classified as primary…
Palmar Lesions and Moth-Eaten Alopecia in a 23-Year-Old Man
A man with suspected but untreated secondary syphilis had nonscarring alopecia, photodistributed facial eruption, oral ulcers, leukopenia, and low C3 level; biopsy of a palmar lesion showed dyskeratotic keratinocytes, basal vacuolar alteration, papillary dermal edema, and perivascular and periappendageal infiltrates…
Adult Male Hypogonadism – A Review
Male hypogonadism is a clinical syndrome of signs and symptoms of testosterone deficiency and consistently low morning serum testosterone concentrations. The prevalence of hypogonadism due to hypothalamus, pituitary, or testes pathology is less than 1%, and the prevalence due to…
Hearing Aids for Adults With Mild to Moderate Hearing Loss
This JAMA Insights discusses hearing aids for adults with mild to moderate hearing loss, including hearing aid function and limitations and prescription vs over-the-counter hearing aid devices.
Lifestyle Modification and Incretin-Based Therapy for Obesity
This JAMA Insights discusses strategies for lifestyle modifications and managing adverse effects for individuals with obesity receiving incretin-based therapies for weight loss.
Primary Care as a Public Utility – The Case for a Common Fund
Importance More than one-third of US adults lack access to primary care, which has increasingly become a commodity rather than the common good envisioned by the National Academies of Sciences, Engineering, and Medicine. Many states are working to bolster primary…
State-Level Abortion Bans and the OBGYN Workforce – A Review of Current Evidence
The US Supreme Courtís June 2022 Dobbs v Jackson Womenís Health Organization (hereafter Dobbs) decision radically changed the landscape of abortion care in the US. As states enacted near-total abortion bans with limited exceptions, critically ill pregnant patients were unable…
