Importance The US Department of Veterans Affairs (VA) Whole Health approach was congressionally mandated in 2016 for patients with chronic pain receiving care in VA hospitals, but no randomized clinical trials have tested its benefits. Objective To evaluate the effectiveness…
Importance Heart failure (HF) affects more than 64 million individuals worldwide, and acute HF is associated with 1-year mortality rates of 23.6% in North America and Europe. Cardiac dyssynchrony from conduction system disease may cause HF progression, particularly in patients…
This JAMA Insights discusses the epidemiology, clinical presentation, and diagnostic evaluation of benign paroxysmal positional vertigo.
Importance Prepregnancy care and counseling optimize maternal health before conception to improve outcomes for mothers and infants. In the US, 66.4% of reproductive-aged women have at least 1 modifiable risk factor for adverse pregnancy outcomes. Observations For all individuals desiring…
Importance Low-cost methods that improve physician adherence to clinical guidelines are lacking. Trauma triage exemplifies time-sensitive conditions where guideline adherence remains at 50% or less despite stakeholder efforts, particularly when treating older adults. Objective To determine whether a theory-based serious…
Importance Previous research has suggested that intrawound vancomycin powder reduces deep surgical site infections among patients with periarticular tibial fractures at high risk of infection. It is unknown whether the addition of tobramycin powder further decreases infection rates. Objective To…
A 52-year-old man had 2 days of cough, dyspnea, and fever. Physical examination showed a rash on the trunk and back with clear vesicles on an erythematous base, imaging showed pulmonary infiltrates, and results of laboratory testing were positive for…
Importance Endometrial cancer accounts for 95% of uterine cancers. Uterine cancers are the fourth most common cancer in women in the US, with an estimated 68 270 new cases and 14 450 cancer deaths projected to occur in 2026. The US mortality…
Importance Colorectal cancer (CRC) risk among older adults with prior adenoma is uncertain. Objective To estimate cumulative CRC risks, non-CRC mortality, and all-cause mortality among adults 75 years of age or older with vs without adenoma at prior colonoscopy (in…
This JAMA Clinical Guidelines Synopsis summarizes the American College of Gastroenterologyís 2025 recommendations on management of Crohn disease in adults.
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