Importance Osteoporosis is characterized by low bone mass, increased bone fragility, and increased susceptibility to fracture, which is associated with substantial morbidity, mortality, and economic costs. Worldwide, 1 in 3 women and 1 in 5 men older than 50 years of…
This JAMA Clinical Guidelines Synopsis summarizes the American College of Cardiology and American Heart Associationís 2024 guidelines on management of lower extremity peripheral artery disease.
Importance West Nile virus (WNV), a neurotropic flavivirus spread by Culex species mosquitoes, is the leading cause of mosquito-borne disease in the contiguous US. From 2014 to 2023, a mean of 1300 WNV neuroinvasive disease cases and 130 deaths were reported annually in…
This JAMA Insights examines the epidemiology, diagnosis, and management of eastern equine encephalitis virus disease in the US following a recent increase in reported cases.
A woman had palpitations, fatigue, and worsening migraines. Plasma normetanephrine concentration was elevated, plasma metanephrine concentration was within reference range, and abdominal magnetic resonance imaging showed a left infrarenal para-aortic mass. What is the diagnosis and what would you do…
Importance Up to 40% of men older than 50 years have lower urinary tract symptoms, including urinary urgency, nocturia, and weak urinary stream, due to disorders of the bladder and prostate. These symptoms negatively affect quality of life and may be…
This JAMA Clinical Guidelines Synopsis summarizes the 2024 Kidney Disease: Improving Global Outcomes (KDIGO) recommendations for management and delaying progression of chronic kidney disease (CKD) in adults.
Importance Early-onset gastrointestinal (GI) cancer is typically defined as GI cancer diagnosed in individuals younger than 50 years. The incidence of early-onset GI cancer is rising globally, and early-onset GI cancers represent the most rapidly increasing early-onset cancer in the US….
Importance Ovarian cancer is the eighth most common cause of cancer and cancer death in women worldwide. In 2022, ovarian cancer was diagnosed in approximately 324,398 individuals, and 206 839 died of ovarian cancer worldwide. In 2025, it is estimated that…
This JAMA Insights discusses evidence about the care of patients with firearm injury, including management of chronic pain, peripheral nerve injury, and lead toxicity from bullet fragments.
© 2026
American Board of Medical Specialties | Policies | Sitemap | Terms of Use | www.abms.org
