JAMA

Balloon Angioplasty vs Medical Management for Intracranial Artery Stenosis – The BASIS Randomized Clinical Trial

Importance  Previous randomized clinical trials did not demonstrate the superiority of endovascular stenting over aggressive medical management for patients with symptomatic intracranial atherosclerotic stenosis (sICAS). However, balloon angioplasty has not been investigated in a randomized clinical trial. Objective  To determine whether balloon…

Scabies, Bedbug, and Body Lice Infestations – A Review

Importance  Scabies, bedbug, and body lice infestations are caused by organisms that live on or in the skin, on clothing, or in the environment and commonly cause pruritus and rash. In 2021, approximately 622 million incident cases of scabies occurred globally….

Evaluation of Suspected Antibiotic Allergies

This JAMA Clinical Guidelines Synopsis summarizes the 2022 recommendations on evaluation of suspected antibiotic allergies from the American Academy of Allergy, Asthma & Immunology and American College of Allergy, Asthma & Immunology.

Community-Acquired Pneumonia – A Review

Importance  Community-acquired pneumonia (CAP) results in approximately 1.4 million emergency department visits, 740 000 hospitalizations, and 41 000 deaths in the US annually. Observations  Community-acquired pneumonia can be diagnosed in a patient with 2 or more signs (eg, temperature >38 °C or ≤36 °C;…

Word Choice and the Patient Encounter

This JAMA Insights in the Communicating Medicine series explores how differences in word choice can affect both visit interactions and visit outcomes in patient encounters.

N-of-1 Studies in an Era of Precision Medicine

This JAMA Insights in the Genomics and Precision Health series examines N-of-1 trials, a term used to describe studies in small numbers of individuals or a single individual treated with genetically targeted interventions.

Chronic Spontaneous Urticaria – A Review

Importance  Chronic spontaneous urticaria affects approximately 1% of the general population worldwide, including approximately 3 million people in the US, impairs patients’ quality of life, and is associated with multiple comorbidities. Observations  Chronic spontaneous urticaria affects patients of any age but is…

Health Care for People Experiencing Homelessness

This JAMA Insights examines the adverse effects of homelessness on physical and mental health and suggests strategies to improve access to health care, services, and housing for people experiencing homelessness.