Importance A patent foramen ovale (PFO), an opening between the right and left atria during normal fetal development that fails to close after birth, is present in approximately 25% of all adults. Paradoxical embolism, a venous thromboembolism that travels to the…
This JAMA Insights explores optimal strategies for managing the adverse effects associated with incretin-based medications for obesity, including semaglutide and tirzepatide.
This JAMA Insights explores strategies for effectively communicating a diagnosis of mild cognitive impairment or dementia to patients and their care partners.
A 34-year-old woman had recurrent episodes of crampy, diffuse abdominal pain not relieved by eating or defecation. Laboratory evaluation was unremarkable except for decreased C4 levels; abdominal computed tomography showed jejunal wall edema and ascites; and her father and brother…
Importance This article highlights key National Institutes of Health (NIH) programs, policies, and scientific advances that have informed and improved the health of women and describe the promise and potential of harnessing cutting-edge science and integrative approaches to advance women’s health…
This JAMA Clinical Guidelines Synopsis summarizes the 2024 Society of Critical Care Medicine guidelines on use of corticosteroids in sepsis, acute respiratory distress syndrome, and community-acquired pneumonia.
Importance Private equity acquisitions of health care facilities have rapidly increased over the past decade. However, little is known about the effects of private equity acquisitions of US hospitals on patient care experience. Objective To evaluate whether the acquisition of hospitals by…
This JAMA Insights explores the prevalence of episodic and chronic migraine in adults and acute and preventive treatments for migraine, such as novel calcitonin gene-related peptide receptor antagonists.
Importance Fragility fractures result in significant morbidity. Objective To review evidence on osteoporosis screening to inform the US Preventive Services Task Force. Data Sources PubMed, Embase, Cochrane Library, and trial registries through January 9, 2024; references, experts, and literature surveillance through July 31,…
Importance Osteoporotic fractures are associated with psychological distress, subsequent fractures, loss of independence, reduced ability to perform activities of daily living, and death. Objective The US Preventive Services Task Force (USPSTF) commissioned a systematic review to evaluate the evidence on the benefits…
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