Importance Understanding health conditions with the most spending and variation across locations and over time is important for identifying trends, highlighting inequalities, and developing strategies for lowering health spending. Objective To estimate US health care spending for each of 3110 US counties,…
This Guide to Statistics and Methods provides an overview of platform trials, describes the characteristics that make them more efficient for evidence generation, and discusses their limitations.
Importance Out-of-hospital cardiac arrest incidence in apparently healthy adults younger than 40 years ranges from 4 to 14 per 100 000 person-years worldwide. Of an estimated 350 000 to 450 000 total annual out-of-hospital cardiac arrests in the US, approximately 10% survive. Observations Among young…
This JAMA Insights discusses the increased risk of coccidioidomycosis due to climate change and the importance of clinicians, patients, and health systems being educated about the disease to ensure accurate identification and optimal care for patients.
Importance Patients in the US have persistent needs for safe, evidence-based care. Physicians in the US report fear of liability risk and the need to practice “defensive medicine.” In 2024, the American Law Institute revised the legal standard for assessing medical…
A 25-year-old man taking no regular medications presented to clinic with a 1-month history of skin lesions, which began as small painless papules on his face and progressed to vesicles and pustules over 1 week. Two weeks prior to presentation,…
This JAMA Insights provides an evidence-based summary for discussing information about breast density with patients, including discussions that involve shared decision-making.
This JAMA Insights explores how coronary artery calcium and computed tomography calcium scores can improve risk assessment for atherosclerotic cardiovascular disease and inform recommendations for statin therapy.
Importance Eating disorders are characterized by disturbances in eating behavior and occur worldwide, with a lifetime prevalence of 2% to 5%. They are more common among females than males and may be associated with medical and psychiatric complications, impaired functioning, and…
This JAMA Insights discusses the need to fully assimilate evidence from observed and projected effects of climate change on health and invest in developing and implementing effective health protection from preventable climate-sensitive conditions.
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