JAMA

Inhaled Pharmacotherapy for Stable COPD

This JAMA Clinical Guidelines Synopsis summarizes the 2025 Global Strategy for the Diagnosis, Management, and Prevention of COPD.

Diagnosis and Treatment of Type 2 Diabetes in Adults – A Review

Importance  Type 2 diabetes involves progressive loss of insulin secretion from pancreatic β cells in the setting of insulin resistance and manifests clinically as hyperglycemia. Type 2 diabetes accounts for 90% to 95% of all cases of diabetes globally, with estimates…

Screening for Intimate Partner Violence and for Caregiver Abuse of Older or Vulnerable Adults – An Evidence Report and Systematic Review for the US Preventive Services Task Force

Importance  Intimate partner violence (IPV) and caregiver abuse of older or vulnerable adults are common and cause significant morbidity. Objective  To review the evidence on screening and interventions for IPV and caregiver abuse among adults. Data Sources  PubMed, Cochrane Library, and EMBASE through…

Forearm Pain and Stiffness in a 34-Year-Old Woman

A 34-year-old woman had progressive skin tightening over her right elbow and forearm, bilateral forearm pain, difficulty extending her fingers and elbows, and elevated eosinophil count and C-reactive protein level; examination showed a linear depression along a superficial vein when…

Osteoporosis – A Review

Importance  Osteoporosis is characterized by low bone mass, increased bone fragility, and increased susceptibility to fracture, which is associated with substantial morbidity, mortality, and economic costs. Worldwide, 1 in 3 women and 1 in 5 men older than 50 years of…

Management of Peripheral Artery Disease

This JAMA Clinical Guidelines Synopsis summarizes the American College of Cardiology and American Heart Associationís 2024 guidelines on management of lower extremity peripheral artery disease.

West Nile Virus – A Review

Importance  West Nile virus (WNV), a neurotropic flavivirus spread by Culex species mosquitoes, is the leading cause of mosquito-borne disease in the contiguous US. From 2014 to 2023, a mean of 1300 WNV neuroinvasive disease cases and 130 deaths were reported annually in…

Eastern Equine Encephalitis in the US

This JAMA Insights examines the epidemiology, diagnosis, and management of eastern equine encephalitis virus disease in the US following a recent increase in reported cases.

A 25-Year-Old With Palpitations, Fatigue, and Migraines

A woman had palpitations, fatigue, and worsening migraines. Plasma normetanephrine concentration was elevated, plasma metanephrine concentration was within reference range, and abdominal magnetic resonance imaging showed a left infrarenal para-aortic mass. What is the diagnosis and what would you do…