A Patient With Prior Skin Cancers and New Diagnosis of Bell Palsy
A 78-year-old man with a history of nonmelanoma skin cancers presented with left-sided upper and lower facial weakness. What is your diagnosis?
ABMS Lifelong Learning CME Activity
Alteplase for Acute Ischemic Stroke at 4.5 to 24 Hours – The HOPE Randomized Clinical Trial
Importance The safety and efficacy of intravenous thrombolytics beyond 4.5 hours after ischemic stroke onset remain inadequately studied. Objective To evaluate the safety and efficacy of intravenous alteplase administered 4.5 to 24 hours after stroke onset in patients with salvageable brain tissue,…
Geroscience – A Translational Review
Importance The incidence of stroke, heart failure, dementia, many cancers, coronary artery disease, and physical disability rise exponentially with age. Geroscience is a relatively new discipline that aims to define and modify aging-related biologic pathways, slow age-related disability, prevent age-related diseases,…
Anterior Segmental Optic Nerve Lesion Following Methanol Poisoning
This case report describes a 61-year-old man with alcohol use disorder who presented with altered consciousness and vision loss after ceasing alcohol consumption.
Screening for Syphilis Infection in Persons With Moth-Eaten Alopecia
This Teachable Moment discusses the importance of recognizing the clinical clue of moth-eaten alopecia for secondary syphilis.
Prostatitis – A Review
Importance Prostatitis is defined as infection, inflammation, or pain of the prostate gland and affects approximately 9.3% of men in their lifetime. Observations Acute bacterial prostatitis consists of a urinary tract infection (UTI) that includes infection of the prostate, typically associated with…
A 34-Year-Old With Recurrent Strokes
A 34-year-old patient with a family history of stroke had right-sided headache, left upper extremity hemiparesis, and left hand numbness; magnetic resonance angiography showed bilateral narrowing of the terminal portion of the intracranial carotid arteries, more severe on the right….
An Eruption of Painful Violaceous Plaques
A man in his 60s with end-stage kidney failure presented with an acute eruption of painful rashes. What is your diagnosis?
Dalbavancin for Treatment of Staphylococcus aureus Bacteremia
Importance Dalbavancin is a long-acting intravenous lipoglycopeptide that may be effective for treatment of complicated Staphylococcus aureus bacteremia without requiring long-term intravenous access. Objective To evaluate the efficacy and safety of dalbavancin vs standard therapy for completion of treatment of complicated S aureus bacteremia. Design, Setting,…
Measles
This JAMA Insights discusses transmission, clinical presentation, and diagnosis of measles and emphasizes the importance of vaccination to protect those at highest risk for complications from measles, including young children and pregnant individuals.
