Growing Congenital Simple Hamartoma of the Retinal Pigment Epithelium
This case report discusses an actively growing congenital simple hamartoma of the retinal pigment epithelium in a patient aged 17 years.
ABMS Lifelong Learning CME Activity
Bilateral Paracentral Corneal Opacity in a Man Aged 22 Years
This case report describes a diagnosis of Schnyder crystalline corneal dystrophy in a man aged 22 years with progressive bilateral corneal opacification over 5 years and no visual symptoms.
Sinus Wall Changes in a Patient With Chronic Rhinosinusitis
A 64-year-old woman with an extensive medical history was referred for continued management of long-standing chronic rhinosinusitis without nasal polyps. What is your diagnosis?
Hemorrhage Into the Canal of Gratiolet
This case report describes a unilateral basal ganglia hemorrhage passing through the anterior commissure within the canal of Gratiolet to the contralateral side.
Immune Thrombotic Thrombocytopenic Purpura – A Review
Importance Immune thrombotic thrombocytopenic purpura (iTTP) is a life-threatening thrombotic microangiopathy that presents with microangiopathic hemolytic anemia (MAHA) and thrombocytopenia. Worldwide annual incidence of iTTP is 2 cases per million to 6 cases per million. Observations Immune TTP is caused by an…
Asymptomatic Yellow-Brown Plaques on the Great Toes
A man in his 30s presented with a 6-month history of asymptomatic yellow-brown plaques on the first digits of his feet that were unresponsive to urea cream and clobetasol treatment. What is your diagnosis?
Remestemcel-L-rknd for Steroid-Refractory Acute Graft-vs-Host Disease in Pediatric Patients
This JAMA Insights discusses the FDA approval of remestemcel-L-rknd to treat graft-vs-host disease in children and provides regulatory considerations for this approval.
Left Ventricular Noncompaction Cardiomyopathy
This case report describes an echocardiography-based diagnosis of left ventricular noncompaction cardiomyopathy in a male patient in his 40s who presented with sudden-onset dyspnea.
Unusual Computed Tomography Finding After Mastoidectomy and Ossiculoplasty
A 20-year-old Chinese male competitive swimmer presented with bilateral conductive hearing loss; single-stage surgery was performed to remove a cholesteatoma. Postoperative computed tomography scans revealed an unusual finding. What is your diagnosis?
Autoamputation in Mismatch Repair–Deficient Colon Cancer
A woman in her 50s with a history of hemochromatosis, psoriasis, and type 2 diabetes presented with a 3-month history of abdominal pain, weight loss, and a large palpable fixed abdominal mass. What is your diagnosis?
