A woman in her 60s, who had undergone hysterectomy, adnexectomy, and concurrent chemoradiotherapy for cervical cancer 8 years prior, presented with a 2-year history of painful pink vesicular and papular lesions on the vulva and thighs. What is your diagnosis?
Importance Anorexia nervosa is a prevalent psychiatric illness associated with exceptionally poor outcomes, including high rates of morbidity and premature mortality. Current evidence-based treatments for anorexia nervosa were developed several decades ago and have limited efficacy. The anorexia nervosa field—and the…
This JAMA Insights discusses trauma-informed care practices that can help clinicians provide sensitive and supportive care that may improve health outcomes in patients with a history of trauma.
This case report describes a 36-year-old male patient with Wilson disease and opposite muscle tone manifestations in his upper and lower limbs.
Importance Sildenafil citrate may increase uteroplacental blood flow. Its ability to reduce perinatal complications related to fetal hypoxia during labor is uncertain. Objective To compare the effectiveness of intrapartum maternal oral sildenafil citrate vs placebo in improving perinatal outcomes potentially related to…
This case report describes a woman in her 60s with hypertrophy of dorsal tongue papillae in a honeycomb pattern along with papillomatous growth of the gingiva.
A man in his early 50s presented with recurrent episodes of cough, palpitations, shortness of breath, and exertional chest pain. What would you do next?
This case report describes a diagnosis of patent foramen ovale in a man in his 60s presenting with stroke symptoms and multifocal infarcts on magnetic resonance imaging of the brain.
Importance Guidelines recommend augmenting enteral protein during critical illness, but the impact on patient outcomes is uncertain. Objective To determine whether augmenting enteral protein increases days alive and free from hospitalization. Design, Setting, and Participants This cluster randomized, crossover, open-label trial recruited critically…
Importance In 2023, the US Department of Health and Human Services (HHS) issued a letter to the administrator of the Drug Enforcement Administration (DEA) recommending rescheduling of cannabis (marijuana) from Schedule I to Schedule III under the Controlled Substances Act (CSA)….
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