A Malignant Premature Atrial Contraction
This case report describes the electrocardiogram findings of a patient in their 60s with lightheadedness and a short episode of numbness.
Journal-based
Diagnosis and Treatment of Acute Appendicitis – 2025 Edition of the World Society of Emergency Surgery Jerusalem Guidelines
Importance Acute appendicitis is the most common abdominal surgical emergency worldwide and a leading cause of emergency hospital admissions and operations. Despite its frequency, substantial variability persists in diagnosis and management across patient populations and health care settings. Objective To provide updated,…
Win Ratio Method for Hierarchical Composite Outcomes in Randomized Clinical Trials
This Guide to Statistics and Methods provides an overview of the win ratio method for analyzing composite end points in randomized clinical trials, including its benefits and limitations.
Neonate With Tense Vesiculobullous Eruptions and Mottled Pigmentation
A neonate presents with a 1-day history of 15 discrete 2- to 10-mm tense and flaccid yellow vesicles and bullae on the chest, arms, and legs as well as subtle flexural erythema but is otherwise well appearing. What is your…
Ann Arbor Guide to Triaging Adults With Suspected Urinary Tract Infection for In-Person and Telehealth Settings
Importance Urinary tract infection (UTI) is common in ambulatory care settings and the primary reason for antibiotic prescribing. Despite several guidelines focused on the type and duration of antibiotics prescribed for treating UTI, there is limited outpatient guidance on how to…
National Pilot Program for Antimicrobial Stewardship in the Republic of Korea
Importance Antimicrobial resistance (AMR) poses an urgent global health challenge, undermining treatment efficacy and threatening patient safety. Antimicrobial stewardship (AMS) programs are recognized as essential interventions to optimize antibiotic use, but implementation has often been fragmented and underresourced. The Republic of…
Traumatic Unilateral Peripheral Arteriolar Occlusions
This case report discusses a diagnosis of peripheral arteriolar sclerosis and nonperfusion in the left eye of a male patient in his 20s after a contusion injury and subsequent treatment for traumatic iritis and ocular hypertension.
Why Should Clinicians Care About Infectious Disease Existential Hazards?
Of all infectious disease events, pandemics could result in significant human depopulation in this Anthropocene epoch or even in the next few centuries. Existential factors that exacerbate pandemic risk include global warming, overpopulation, habitat loss, permafrost thawing, geopolitical conflict, and…
Why and How Should Physicians Mitigate Threats of Nuclear War?
Most physicians do not see, or learn to see, nuclear war threat mitigation as within the scope of their professional duties. This commentary on a case argues there are 2 reasons why physicians, in particular, should draw on their unique…
Why Should Extinction Medicine Be a Specialty?
This commentary on a case builds on recent literature on climate change, health, and human extinction to argue in favor of a new clinical specialty: extinction medicine. If based on precise application of scientific findings about species extinction, disaster prevention…
