Pedunculated Palpebral Conjunctival Papilloma
This case report describes the diagnosis and treatment of conjunctival papilloma in a patient aged 54 years who presented with a 3-month history of a painless lower left eyelid lesion.
Journal-based
Navigating Postacute Care Options for Patients After Hospital Discharge – A Review
Importance Approximately 25% to 40% of hospitalized adults are discharged to receive postacute care (PAC) either at home through home health (HH) or in skilled nursing facilities (SNFs), inpatient rehabilitation facilities (IRFs), or long-term acute care hospitals (LTACHs). An overview of…
Abdominal Clonus in the Setting of a T5 Spinal Cord Injury
This case report describes abdominal clonus diagnosed in a man aged 49 years with a history of a T5 spinal cord injury, kidney dysfunction, and obesity who presented with worsening involuntary movements of the abdomen.
Restless Legs Syndrome – A Review
Importance Restless legs syndrome (RLS) is a sleep-related movement disorder that affects approximately 3% of US adults to a clinically significant extent and can cause substantial sleep disturbance. Observations Restless legs syndrome is characterized by an overwhelming urge to move the limbs,…
Prospects of GLP-1 Therapies for Addiction and Mental Health Comorbidities—Quo Vadis? A Review
Importance Glucagon-like peptide-1 (GLP-1) therapies have revolutionized the management of chronic conditions like obesity and diabetes. Consistent with the overlap between feeding and metabolic pathways and those mediating addictive behaviors, growing evidence suggests that GLP-1 therapies may also be beneficial for…
Management of Opioid Use Disorder
This JAMA Clinical Guidelines Synopsis summarizes the 2024 Canadian Research Initiative in Substance Matters (CRISM) guideline on management of opioid use disorder (OUD).
Nail Sarcoidosis
This case report describes a man in his 30s who was referred for the evaluation of a 3-month destructive process affecting the nail matrix and nail plate of the left thumbnail.
Cost-Effectiveness of Adjuvant Immunotherapy in Cancer Treatments – A Systematic Review
Importance Adjuvant immunotherapy is increasingly integrated into cancer care to reduce recurrence and improve survival. However, its high cost raises critical concerns regarding affordability and economic value across diverse health system contexts. Objective To synthesize published economic evaluations of adjuvant immunotherapy and…
Progressive Left Mandibular Swelling in a Young Man
A 36-year-old man with a 4-year history of Crohn disease who was receiving maintenance therapy with infliximab presented with 6 months of progressive left mandibular pain and swelling. What is your diagnosis?
IgA Nephropathy in Adults – A Review
Importance IgA nephropathy (IgAN) is a chronic kidney disease involving deposition of IgA-containing immune complexes in the glomerulus, causing glomerular inflammation and scarring. It is the most common immune-mediated glomerular disease worldwide, and affects an estimated 198 887 to 208 184 persons in…
