A Patient With Recurrent Pleomorphic Adenomas
A 31-year-old female presented with a progressively enlarging left submandibular mass and history of pleomorphic adenoma of the left submandibular gland. What is your diagnosis?
Journal-based
A Woman With Rheumatoid Arthritis and Vesicular Rash
A patient receiving adalimumab for rheumatoid arthritis had ulcerated plaques on the anterior and lateral aspects of the neck, upper chest, and nape and erythroderma on the dorsum of the hands, corresponding to areas of sun exposure, as well as…
Generalized Dystonia and Defects in Dopaminergic System With Methylmalonic Acidemia
This case report describes generalized dystonia and dopaminergic system involvement in a woman with methylmalonic acidemia.
A Shark-Fin Pattern on the Electrocardiogram
This case report describes a patient in his early 60s with a history of poorly controlled hypertension and hyperlipidemia who presented with paroxysmal chest pain for 2 days.
Gastric Cancer A Review
Importance Globally, 968 350 new cases and 659 853 deaths from gastric cancer were reported in 2022. In the US, 30 300 new cases and 10 780 deaths were estimated in 2025. Observations Gastric cancer is more common in men, and the median age at diagnosis…
PostñIntensive Care Syndrome
This JAMA Insights discusses postñintensive care unit syndrome, including how it is assessed and diagnosed as well as suggestions for treatment and prevention.
Evaluation of the Validity of International Classification of Diseases Codes for Dermatologic Conditions A Systematic Review
Importance Accurate classification of dermatologic conditions using International Classification of Diseases (ICD) codes is essential for research that uses large administrative datasets. Misclassification can be associated with biased epidemiologic estimates and misleading conclusions in population-based studies. Objective To systematically identify and evaluate validated…
Sibling Comparisons to Account for Confounding in Observational Studies
This JAMA Guide to Statistics and Methods explains how sibling analysis can be used to account for confounding in observational studies, using the example of a study on acid suppressants during pregnancy and risk of neuropsychiatric disorders in offspring.
Generalized Atrophic Papules and Acute Abdominal Pain
An adolescent female presented with 3 days of progressive abdominal pain and reported that a rash first appeared nearly 1 year earlier on her left wrist and gradually spread over several weeks. What is your diagnosis?
Exertional Syncope in a Female Teenage Student
A previously healthy female teenager presents with chest tightness and syncope after exertion. Electrocardiogram results showed ST-segment elevation in leads V1 through V4, aVL, and aVR, and laboratory results indicated elevated cardiac troponin T levels. What would you do next?
