Large Bilateral Exudative Retinal Detachments Related to Checkpoint Inhibitors
This case report discusses a diagnosis of exudative retinal detachment secondary to melanoma immunotherapy with the checkpoint inhibitors ipilimaud and nivolumab.
Journal-based
Sexual Health in Cancer Care—A Gap in Understanding
This Teachable Moment describes the need to identify individualized preferences, including sexual health, and mitigate assumptions to avoid unintentional harm done to patients during care.
A Clinical Practice Guideline for the Management of Pregnancy Alloimmunized to Red Blood Cell Antigens
Importance Red blood cell alloimmunization is typically associated with the transplacental transfer of incompatible fetal red blood cells into maternal circulation. Subsequent pregnancies can be affected by fetal anemia, hydrops fetalis, and perinatal death. Most cases of Rhesus D (RhD) alloimmunization…
Continuous Glucose Monitoring
This JAMA Insights discusses continuous glucose monitoring use among individuals with type 2 diabetes, including types of devices, evidence of effectiveness, and adverse effects and contraindications.
Interhemispheric Bullet Migration—A Surgical Dilemma
A 52-year-old male with a history of depression was admitted for confusion, visual hallucinations, and persecutory delusions. Neurological examination revealed temporal disorientation without focal deficits.
Autophagy in Stress-Induced Neuropsychiatric Disorders and Depression
This article discusses how autophagic mechanisms mediate neurobiological and behavioral changes in stress-induced neuropsychiatric disorders and depression.
Therapeutic Use of Cannabis and Cannabinoids – A Review
Approximately 27% of adults in the US and Canada report having ever used cannabis for medical purposes. An estimated 10.5% of the US population reports using cannabidiol (CBD), a chemical compound extracted from cannabis that does not have psychoactive…
A Contemporary Look at the Landscape of Treatment of Tricuspid Regurgitation – A Review
Importance Untreated severe tricuspid regurgitation carries a poor prognosis. We aim to provide a contemporary review of the anatomy, clinical manifestations, and diagnostic and management strategies, including medical, surgical and transcatheter options. By synthesizing current knowledge, this review seeks to equip…
Standardization of Lesion Classification and Assessment by Investigators in Clinical Trials for Hidradenitis Suppurativa – A Consensus Exercise Using a Modified Delphi Approach
Importance Accurate classification and reliability in assessment for lesions of hidradenitis suppurativa (HS) by investigators is critical to the determination of responder status and to overall data quality in clinical trials. Objective To establish consensus-based morphological definitions of HS lesions and guidance…
Hereditary Leukonychia Associated With GJA1 Mutation
This case report describes a woman in her 30s with porcelain-white discoloration of all nails, which persisted under pressure, and a GJA1 mutation.
