Importance Red blood cell alloimmunization is typically associated with the transplacental transfer of incompatible fetal red blood cells into maternal circulation. Subsequent pregnancies can be affected by fetal anemia, hydrops fetalis, and perinatal death. Most cases of Rhesus D (RhD) alloimmunization…
This JAMA Insights discusses continuous glucose monitoring use among individuals with type 2 diabetes, including types of devices, evidence of effectiveness, and adverse effects and contraindications.
A 52-year-old male with a history of depression was admitted for confusion, visual hallucinations, and persecutory delusions. Neurological examination revealed temporal disorientation without focal deficits.
This article discusses how autophagic mechanisms mediate neurobiological and behavioral changes in stress-induced neuropsychiatric disorders and depression.
Approximately 27% of adults in the US and Canada report having ever used cannabis for medical purposes. An estimated 10.5% of the US population reports using cannabidiol (CBD), a chemical compound extracted from cannabis that does not have psychoactive…
Importance Untreated severe tricuspid regurgitation carries a poor prognosis. We aim to provide a contemporary review of the anatomy, clinical manifestations, and diagnostic and management strategies, including medical, surgical and transcatheter options. By synthesizing current knowledge, this review seeks to equip…
Importance Accurate classification and reliability in assessment for lesions of hidradenitis suppurativa (HS) by investigators is critical to the determination of responder status and to overall data quality in clinical trials. Objective To establish consensus-based morphological definitions of HS lesions and guidance…
This case report describes a woman in her 30s with porcelain-white discoloration of all nails, which persisted under pressure, and a GJA1 mutation.
Advances in epigenetic age estimation are now applied in actuarial science to make risk assessment more precise. But such health insurance underwriting practices pose ethical and legal questions about discrimination, privacy, and equity in biological data use. Legal adaptations, such…
Documenting one’s assessment of a patient’s physical appearance during a clinical encounter is regarded as a key element in a clinician’s overall judgment of a patient’s health. This article considers ethically and clinically relevant uses and misuses of such appraisals…
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