Asymptomatic Irregular Pigmented Lesions of the Vulva
A 9-year-old girl presented with a 4-year history of asymptomatic, irregular pigmented lesions on the vulva and was initially diagnosed with a nevus.
Journal-based
Axenfeld-Rieger Syndrome in an Infant
This case report discusses a diagnosis of Axenfeld-Rieger syndrome in an 8-month-old infant who presented with bilateral abnormal pupils, posterior embryotoxon, and dental abnormalities.
Barriers and Consequences of Prior Authorization for Neurologic Medications – A Scoping Review
Importance Prior authorization (PA) is widely used by insurers to control health care costs and promote high-value care, but it can create significant barriers to accessing medications. This is particularly concerning in neurology, where timely treatment is critical to avoid disease…
Optical Coherence Tomography for Carotid Free-Floating Thrombus
This case report describes 2 cases of patients presenting with aphasia diagnosed with free-floating carotid thrombi detected via optical coherence tomography.
Consensus-Harmonized Neuropsychological Assessment for Vascular Cognitive Impairment and Dementia
Importance Harmonization of neuropsychological assessment for vascular cognitive impairment and dementia (VCID) is important for ensuring the highest standards and consistency of diagnosis. A battery proposed in 2006 by the National Institute for Neurological Disorders and Stroke and the Canadian Stroke…
Rationale, Design, and Baseline Clinical Characteristics of the Ziltivekimab Cardiovascular Outcomes Trial
Importance Cardiovascular inflammation is a major determinant of atherosclerotic disease, and inhibition of the central signaling cytokine, interleukin 6 (IL-6), is a promising target for intervention. Patients with chronic kidney disease (CKD) commonly have plasma elevations of inflammatory biomarkers, such as…
Implementing Precision Medicine in Psychiatry
Importance Neuropsychiatric disorders impose a substantial burden on individuals and societies worldwide. Despite significant advances in the understanding of the brain, only a handful of mechanism-based treatments for psychiatric disorders have been discovered and validated in the past 50 years. Observations After…
Acne in Transmasculine Patients – A Scoping Review
Importance Compounded with barriers to care, stigmatization, lack of trust, and high rates of psychiatric comorbidities, transmasculine patients face a high psychosocial burden from acne. Acne is a common sequela of masculinizing hormone therapy, and understanding its epidemiology may improve care…
A 65-Year-Old With Fatigue, Nausea, and Electrocardiogram Abnormalities
A previously healthy man had headache, chest pain, abdominal pain, vomiting, and diarrhea 1 hour after eating raw tuna sashimi. His blood pressure was 67/42 mm Hg, and he had an erythematous nonpruritic rash on his upper torso, ST-segment elevation…
Broad-Spectrum Abnormal Localized Photosensitivity Syndrome
This case report describes a man in his 50s with broad-spectrum abnormal localized photosensitivity syndrome.
