JAMA Surgery

Management of Perforated Peptic Ulcer – A Review

Importance  Perforated peptic ulcer disease (PUD) affects 4 million people annually worldwide, with a lifetime prevalence of 5% to 10%. Of those affected, 5% will progress to the point of perforation. Despite advances in the understanding and treatment, perforated PUD continues…

Radiomics for Treatment Planning in Liver Cancers

This Surgical Innovation delves into the transformative potential of radiomics in liver cancer treatment, highlighting its advancements in pretreatment prognosis, noninvasive tumor profiling, and treatment response prediction, thus paving the way for more personalized therapeutic strategies.

Wearable Intraoperative Augmented Reality for Surgery

This Surgical Innovation explores the potential that wearable augmented reality devices have for improving intraoperative imaging, patient outcomes, and surgical workflows.

Molecular Testing and Targeted Therapies in Hepatobiliary Cancers – A Review

Importance  Hepatobiliary cancers are heterogeneous and molecularly complex. Recent advances in next-generation sequencing (NGS) have enhanced the understanding of their molecular landscape and enabled deployment of biomarker-based gene- and immune-targeted therapies. This review examines the role of molecular testing and targeted…

Autonomic Neural Blockade in Minimally Invasive Surgery

This article discusses the use of intraoperative autonomic neural blockade as a technique to manage postoperative visceral pain and symptoms of postoperative nausea and vomiting in minimally invasive surgery.

Imaging in Diagnosis and Active Surveillance for Prostate Cancer – A Review

Importance  Active surveillance (AS) has become an increasingly important option for managing low-risk and select intermediate-risk prostate cancer. Although imaging, particularly multiparametric magnetic resonance imaging (mpMRI), has emerged in the prebiopsy pathway for the diagnosis of prostate cancer, the role of…

HistotripsyóA Novel and Intriguing Technique of Liver Ablation

This article discusses the use of histotripsy as a noninvasive method for tumor ablation that involves mechanical destruction of tissues without the generation of heat, resulting in accurate and precise treatment without surrounding tissue damage.