JAMA

A Young Woman With Headaches and Peripheral Vision Loss

A 30-year-old nulliparous woman with obesity and history of migraines and depression had 1 month of daily headaches, transient bilateral visual blurring, persistent vision loss in the temporal region of one eye, pulsatile tinnitus, and mild bilateral papilledema. What is…

Working With Medical Interpreters

This JAMA Insights discusses the important role that interpreters play in facilitating communication between patients with limited English-language proficiency and their health care team and provides steps that can be taken to improve communication with remote interpreters for patients.

Calcific Aortic Stenosis – A Review

Importance  Calcific aortic stenosis (AS) restricts the aortic valve opening during systole due to calcification and fibrosis of either a congenital bicuspid or a normal trileaflet aortic valve. In the US, AS affects 1% to 2% of adults older than 65…

Management of Atrial Fibrillation

This JAMA Clinical Guidelines Synopsis summarizes the 2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation.

Diagnosis and Treatment of Polycythemia – A Review

Importance  Polycythemia vera (PV), a myeloproliferative neoplasm characterized by an increased red blood cell mass and increased risk of thrombosis, affects approximately 65 000 people in the US, with an annual incidence of 0.5 to 4.0 cases per 100 000 persons. Observations  Erythrocytosis (hemoglobin…

Harm Reduction Strategies for People Who Use Drugs

This JAMA Insights explores harm reduction strategies for people who use drugs and the clinicians who treat them to help reduce the risk of unintentional drug overdose and infection.

Differential Legal Protections for Biologics vs Small-Molecule Drugs in the US

Importance  Biologics approved by the US Food and Drug Administration (FDA) receive 12 years of guaranteed protection from biosimilar competition compared with 5 years of protection from generic competition for new small-molecule drugs. Under the 2022 Inflation Reduction Act, biologics are…