Importance When randomized trials are unavailable or not feasible, observational studies can be used to answer causal questions about the comparative effects of interventions by attempting to emulate a hypothetical pragmatic randomized trial (target trial). Published guidance to aid reporting of…
A 3-month-old infant presented with a painless, gradually enlarging swelling in their right orbital and temporal region. What is your diagnosis?
Importance Approximately 93 million computed tomography (CT) examinations are performed on 62 million patients annually in the United States, and ionizing radiation from CT is a known carcinogen. Objective To project the number of future lifetime cancers in the US population associated…
Screen use, the time spent engaging with electronic devices such as mobile phones and tablets, can become addictive when individuals experience difficulty stopping despite attempts to do so, as well as symptoms of withdrawal, tolerance, conflict, and relapse (Box). Adolescence…
Importance It has been stated that especially with the advancements in imaging, systemic therapy, and local radical treatment (LRT) that patients with synchronous oligometastatic disease (sOMD) can potentially benefit from curative-intent treatment. This statement is challenged by the results of the…
Importance Although tirzepatide and semaglutide were shown to reduce weight in randomized clinical trials, data from head-to-head comparisons in populations with overweight or obesity are not yet available. Objective To compare on-treatment weight loss and rates of gastrointestinal adverse events (AEs) among…
Importance The role of pesticide exposure from golf courses in Parkinson disease (PD) risk remains unclear. Objective To assess whether proximity to golf courses is associated with increased PD risk and to use information on groundwater vulnerability and municipal well locations to…
This case report describes a 58-year-old patient presenting with seizures and undergoing craniotomy, during which a live parasitic worm was discovered.
The key to reducing unnecessary work is to involve the entire care team in sharing the workload. This microlesson provides collaborative strategies to maintain patient care workflows while freeing up physician time to enhance the focus on patient interactions.
Physician burnout is an epidemic in the US health care system and it is vital to stop the unnecessary workload that physicians face to improve practice efficiency and lead to an improved culture at the organizational level. This microlesson provides…
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