Importance SARS-CoV-2 remains a substantial cause of respiratory illness, morbidity, and mortality. Evidence to date has demonstrated that COVID-19 vaccines reduce the risk of severe disease, including hospitalization and death. Objective This systematic review identifies and summarizes newly published studies…
Importance Obstructive sleep apnea (OSA) affects nearly 1 billion adults worldwide and is independently associated with cardiovascular disease, stroke, and increased mortality. While continuous positive airway pressure (CPAP) remains the criterion standard treatment, adherence rates of only 30% to 60%…
A 13-year-old boy presented to the oral medicine clinic with a 3-year history of oral erosions resistant to treatment with topical steroids and mouthwashes. What is your diagnosis?
A 35-year-old man with a history of coronary heart disease was hospitalized due to palpitations and had a hypodense nodule in the right thyroid lobe with mild enhancement and bilateral cervical lymphadenopathy. What is your diagnosis?
A 76-year-old man presented to the emergency department with 5 days of worsening dyspnea at rest, lower extremity edema, fatigue, confusion, and poor oral intake. What is your diagnosis?
This case report describes a woman in her 70s whose initial electrocardiogram (ECG) suggested ventricular tachycardia but presented asymptomatically to the emergency department.
This Clinical Insights provides an overview of screening for and treating primary aldosteronism, including information on how medications may affect laboratory test results.
Importance Clonal hematopoiesis of indeterminate potential (CHIP) has emerged as an independent and potent cardiovascular risk factor. As genetic sequencing becomes more widespread and the population ages, the identification of CHIP will increase substantially. Despite strong epidemiologic and mechanistic evidence…
Importance In February 2025, Australia introduced maternal vaccination with bivalent respiratory syncytial virus prefusion F protein–based vaccine (RSVpreF) in the National Immunization Program for pregnant individuals from 28 weeks’ gestation as the primary, year-round strategy to prevent RSV disease in…
Importance National organizations recommend antiviral treatment for hospitalized children with influenza; however, use in this setting has recently declined. Studies of oseltamivir effectiveness in children are limited by misclassification bias, unknown symptom onset date, and incomplete capture of antiviral use…
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