This case report discusses a diagnosis of conjunctival Kaposi sarcoma in a male patient aged 26 years with a history of advanced HIV infection who presented with a painless red conjunctival nodule.
A 20-year-old woman had, since age 8 years, a lesion on the left side of her face that had slowly progressed over 12 years, causing facial asymmetry. Examination revealed an ill-defined soft tissue mask, and imaging showed bone involvement. What…
Importance There is no international consensus on defining vitiligo severity or relapse. Current measures (such as body surface area) quantify depigmentation but do not fully capture the broader clinical and psychosocial effects of the disease. Objective To develop internationally agreed-upon…
Clinical Question Among adults with moderate to severe plaque psoriasis, how do systemic treatments compare in attaining a Psoriasis Area and Severity Index 90 (PASI 90) response and the occurrence of serious adverse events? Bottom Line Biologic therapies, particularly interleukin…
A woman in her 60s presented with a 3-year history of pulmonary arterial hypertension and 2-month history of worsening dyspnea and progressive abdominal distension. What is your diagnosis?
This cohort study evaluates physician revenue, patient volumes, and claim denials among adopters and nonadopters of artificial intelligenceñbased clinical documentation tools in one health system.
Importance Disparities by race and socioeconomic status in cardiometabolic diseases are prevalent, and social determinants of health (SDOH) are significant contributors to these disparities. However, SDOH research often focuses on negative factors. Objective To examine associations of volunteering, a potentially…
Importance A previous study showed a high prevalence of central sensitization syndrome (CSS) in patients with autonomic symptoms. The prevalence of CSS in postural tachycardia syndrome (POTS), a form of dysautonomia, is unknown. Objectives To analyze the prevalence of CSS…
Importance Public reporting of outcomes increases transparency. Research on the association between public reporting programs and quality of care and outcomes is needed. Objective To evaluate whether hospital voluntary participation in the Get With The Guidelines (GWTG)–Stroke public reporting program…
Importance The clinical benefit of opportunistic genomic screening for familial hypercholesterolemia (FH) has not been demonstrated in a randomized clinical trial (RCT). Objective To evaluate the impact of returning clinically confirmed FH-associated genetic results on low-density lipoprotein cholesterol (LDL-C) levels….
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