Activity

Activity ID

14938

Expires

March 25, 2029

Format Type

Journal-based

CME Credit

1

Fee

$30

CME Provider: JAMA Dermatology

Description of CME Course

Clinical Question  Among adults with moderate to severe plaque psoriasis, how do systemic treatments compare in attaining a Psoriasis Area and Severity Index 90 (PASI 90) response and the occurrence of serious adverse events?

Bottom Line  Biologic therapies, particularly interleukin (IL)–17 and IL-23 inhibitors, provide the highest short-term likelihood of achieving PASI 90, while existing oral agents offer more modest efficacy but remain important options for patients who prefer noninjectable treatments. Severe adverse events were uncommon across all therapies and similar to placebo in the short term.

Disclaimers

1. This activity is accredited by the American Medical Association.
2. This activity is free to AMA members.

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More Information
Commercial Support?
No

NOTE: If a Member Board has not deemed this activity for MOC approval as an accredited CME activity, this activity may count toward an ABMS Member Board’s general CME requirement. Please refer directly to your Member Board’s MOC Part II Lifelong Learning and Self-Assessment Program Requirements.

Educational Objectives

To identify the key insights or developments described in this article

Keywords

Dermatology, Psoriasis

Competencies

Medical Knowledge

CME Credit Type

AMA PRA Category 1 Credit

DOI

10.1001/jamadermatol.2026.0200

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