Activity ID
14938Expires
March 25, 2029Format Type
Journal-basedCME Credit
1Fee
$30CME Provider: JAMA Dermatology
Description of CME Course
Clinical Question Among adults with moderate to severe plaque psoriasis, how do systemic treatments compare in attaining a Psoriasis Area and Severity Index 90 (PASI 90) response and the occurrence of serious adverse events?
Bottom Line Biologic therapies, particularly interleukin (IL)–17 and IL-23 inhibitors, provide the highest short-term likelihood of achieving PASI 90, while existing oral agents offer more modest efficacy but remain important options for patients who prefer noninjectable treatments. Severe adverse events were uncommon across all therapies and similar to placebo in the short term.
Disclaimers
1. This activity is accredited by the American Medical Association.
2. This activity is free to AMA members.
ABMS Member Board Approvals by Type
ABMS Lifelong Learning CME Activity
Allergy and Immunology
Anesthesiology
Colon and Rectal Surgery
Family Medicine
Medical Genetics and Genomics
Nuclear Medicine
Ophthalmology
Pathology
Physical Medicine and Rehabilitation
Plastic Surgery
Preventive Medicine
Psychiatry and Neurology
Radiology
Thoracic Surgery
Urology
Commercial Support?
NoNOTE: If a Member Board has not deemed this activity for MOC approval as an accredited CME activity, this activity may count toward an ABMS Member Board’s general CME requirement. Please refer directly to your Member Board’s MOC Part II Lifelong Learning and Self-Assessment Program Requirements.
Educational Objectives
To identify the key insights or developments described in this article
Keywords
Dermatology, Psoriasis
Competencies
Medical Knowledge
CME Credit Type
AMA PRA Category 1 Credit
DOI
10.1001/jamadermatol.2026.0200