Prevalence of Youth Overweight, Obesity, and Severe Obesity
This cross-sectional study investigates the prevalence of overweight, obesity, and severe obesity among US youths aged 0 to 19 years in 2024.
ABMS Lifelong Learning CME Activity
Identifying Household Diabetes Risk for Family Diabetes Prevention Using Electronic Health Records
This cohort study uses electronic health record (EHR) data to evaluate diabetes risk factors among household members of adults with prediabetes.
Peer Navigator Intervention and Opioid-Related Adverse Events for Emergency Department Patients – A Randomized Clinical Trial
Importance Emergency departments (EDs) serve patients at high risk for overdose. There is increasing interest in peer-delivered ED interventions for substance use but little rigorous research on their effectiveness. Objective To examine the effectiveness of an initiative (Relay) operated by…
Feasibility of an Indigenous Food Is Medicine Program for Patients With Heart Failure in Rural Navajo Nation – The MUTTON-HF Nonrandomized Clinical Trial
Importance The ongoing consequences of settler colonialism produce adverse structural drivers, particularly nutrition insecurity, that contribute to cardiovascular health disparities among Indigenous populations. There is increased focus in Native communities to reclaim traditional precontact foods to improve health. Therefore, a…
Machine Learning–Guided Detection of Malignancy of Lung Nodules With Molecular Imaging–Guided Surgery
Importance Over 1 million pulmonary nodules are discovered each year in the US, and many of these undergo molecular imaging–guided surgery to obtain a diagnosis. Locating a small nodule and determining its malignant potential is technically challenging and is prone…
Genetic Predisposition to Excess Body Weight and Survival in Women Diagnosed With Breast Cancer
Importance Excess body weight, which is associated with poor survival after breast cancer (BC) diagnosis, is a heritable trait. Objective To investigate whether genetic predisposition to excess body weight is associated with the risk of mortality among BC survivors. Design,…
Diagnosis and Management of Resistant Hypertension – A Review
Hypertension, defined as office systolic blood pressure (SBP) 130 mm Hg or greater and/or diastolic blood pressure 80 mm Hg or greater, affects 43.9% of women and 49.5% of men in the US. Approximately 19.7% of patients treated for hypertension…
Adherence to Healthy Lifestyle and Risk of Cardiometabolic Diseases in Individuals With Hypertension
Importance Hypertension significantly increases the risk of cardiovascular diseases (CVDs) and related cardiometabolic conditions, yet the role of healthy lifestyle in modifying these risks remains underexplored. Objective To investigate associations of adherence to healthy lifestyle before and after a hypertension…
Time of Detection of Liver Metastases and Survival in Patients With Colorectal Cancer
Importance Colorectal cancer liver metastases (CRLM) are a common manifestation of colorectal cancer, and clinical decision-making for these patients is complex. The timing of CRLM detection, defined as synchronous, early metachronous, or late metachronous, is hypothesized to influence survival outcomes,…
Treating Opioid Use Disorder With Methadone in Pharmacies
Importance Methadone, a medication for opioid use disorder, is underused in the US response to the opioid overdose crisis. Under federal law, methadone can be offered in pharmacies via medication units, although a change to federal statutes or regulations could…
