Metabolic dysfunction–associated steatotic liver disease (MASLD; formerly nonalcoholic fatty liver disease) is a growing cause of chronic liver disease, affecting 25% of the population in the US and 30% of the population globally.1 It is the second leading indication for liver…
Importance Advancements in molecular engineering have facilitated the creation of engineered T cells that express synthetic receptors, termed chimeric antigen receptors (CARs). This is promising not only in cancer treatment but also in addressing a spectrum of other conditions. This review provides a…
This JAMA Insights explores several aspects of dengue virus infection, including epidemiology, diagnosis, and clinical management, following a global resurgence in both endemic and nonendemic regions.
A 12-year-old boy with no relevant medical history presented with a left maxillary gingival swelling of 4 years duration associated with palatal tipping of the left maxillary central incisor. What is your diagnosis?
This case report describes a teenage girl with glistening hair and was found to have alternating dark and light bands within the hair shafts on trichoscopic evaluation.
Importance Central nervous system (CNS) metastases presenting as either brain parenchymal metastases or leptomeningeal metastases are diagnosed in up to 50% of patients with advanced non–small cell lung cancer during their disease course. While historically associated with a poor prognosis due…
Internationally, there is a long history of improving dementia care quality by focusing on patients’ strengths and supporting environments that normalize their daily routines. The European dementia village is a pioneering health care site: 4 acres of integrated housing and…
Importance New data and new antiretroviral drugs and formulations continue to become available for the prevention and management of HIV infection. Objective To provide updated recommendations for HIV treatment and clinical management and HIV prevention. Methods A panel of volunteer expert physician scientists…
Design is and always has been interventional and clinically relevant. Modern evidence-based designers’ lineage was prominently shaped between 1800 and 1970. This article investigates hospital designs during this period that were correlated with patients’ health outcomes and suggests how this…
This case report describes a man in his 60s with hypertension, deep vein thrombosis, and a recent diagnosis of HIV presented with low CD4 cell count after starting antiretroviral therapy with tenofovir alafenamide-emtricitabine-bictegravir.
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