Journal-based

Pediatric Patient Referred for an Optic Nerve Mass

A 13-year-old male patient was referred for evaluation of an optic nerve mass with decreased central vision and occasional pain. Examination revealed an afferent pupillary defect, a few vitreous cells, and an optic nerve lesion associated with a small peripapillary…

Granulomatous Cheilitis in a Young Woman

This case report describes a young woman with a diffusely swollen lower lip, normal tongue, and no history of local trauma, irritants, or allergies.

Digital Health Technology Research Funded by the National Institutes of Health

Importance  Digital health in biomedical research and its expanding list of potential clinical applications are rapidly evolving. A combination of new digital health technologies (DHTs), novel uses of existing DHTs through artificial intelligence– and machine learning–based algorithms, and improved integration and…

Recent Developments in Women’s Health Research at the US National Institutes of Health

Importance  This article highlights key National Institutes of Health (NIH) programs, policies, and scientific advances that have informed and improved the health of women and describe the promise and potential of harnessing cutting-edge science and integrative approaches to advance women’s health…

Smooth, Firm, Skin-Colored Papules on the Nasal Dorsum

A healthy 19-year-old man with Fitzpatrick skin type V presented with a 2-year history of smooth, firm, skin-colored papules on the nasal dorsum and bilateral alae. What is your diagnosis?

Practical Guide to Clinical Big Data Sources

This Guide to Statistics and Methods summarizes the limitations and considerations when using large datasets comprising patient-level data, typically abstracted from institutional electronic health records, in health services research.