Journal-based

Fever and Floaters in a 56-Year-Old Woman

A 56-year-old woman presents with fever, headache, nausea, and vomiting. Computed tomography scan of the head shows multiple coarse, dystrophic calcifications, and she reports floaters with normal vision. What would you do next?

A Unified Approach to Health Data Exchange – A Report From the US DHHS

Importance  Health information technology, such as electronic health records (EHRs), has been widely adopted, yet accessing and exchanging data in the fragmented US health care system remains challenging. To unlock the potential of EHR data to improve patient health, public health,…

A 61-Year-Old Man With Weakness and Gait Dysfunction

A man aged 61 years presented with chronic progressive weakness and gait dysfunction over a 4-year period. He had Ashkenazi Jewish ancestry and a history of memory loss, inappropriate laughter, dysarthria, and hypertension. Examination revealed impaired recall, extremity spasticity, distal…

Care for Patients With a History of Immigration

This JAMA Insights explores how considering clinical factors and/or potential exposures during the premigration, migration, and postmigration phases of immigration could help clinicians more effectively treat patients born outside the US.

Disseminated Pseudovesicles in an Immunocompromised Patient

A 41-year-old immunocompromised man presented to the intensive care unit with neutropenic fevers, and after a 1-week stay, developed oral ulcers and tender, diffuse, erythematous pseudovesicular papules, many umbilicated, on the face, trunk, and extremities. What is your diagnosis?

Essential Thrombocythemia – A Review

Importance  Essential thrombocythemia, a clonal myeloproliferative neoplasm with excessive platelet production, is associated with an increased risk of thrombosis and bleeding. The annual incidence rate of essential thrombocythemia in the US is 1.5/100 000 persons. Observations  Patients with essential thrombocythemia have a persistent…

Palliative Care Program for Community-Dwelling Individuals With Dementia and Caregivers – The IN-PEACE Randomized Clinical Trial

Importance  Care management benefits community-dwelling patients with dementia, but studies include few patients with moderate to severe dementia or from racial and ethnic minority populations, lack palliative care, and seldom reduce health care utilization. Objective  To determine whether integrated dementia palliative care…