JAMA

Apixaban to Prevent Recurrence After Cryptogenic Stroke in Patients With Atrial Cardiopathy – The ARCADIA Randomized Clinical Trial

Importance  Atrial cardiopathy is associated with stroke in the absence of clinically apparent atrial fibrillation. It is unknown whether anticoagulation, which has proven benefit in atrial fibrillation, prevents stroke in patients with atrial cardiopathy and no atrial fibrillation. Objective  To compare anticoagulation…

Management of Food Allergies and Food-Related Anaphylaxis

Importance  An estimated 7.6% of children and 10.8% of adults have IgE-mediated food-protein allergies in the US. IgE-mediated food allergies may cause anaphylaxis and death. A delayed, IgE-mediated allergic response to the food-carbohydrate galactose-α-1,3-galactose (alpha-gal) in mammalian meat affects an estimated…

Delivering Effective Messages in the Patient-Clinician Encounter

This JAMA Insights discusses the importance of effective patient-clinician communication and provides strategies for clinicians that can enhance accurate information gathering and exchange, encourage patient engagement, enhance comprehension, and ensure retention of the information.

Management of Candida

This JAMA Insights Clinical Update discusses the diagnosis, treatment, prognosis, and infection-prevention measures for Candida auris.

An Incarcerated Individual With Weight Loss and Interstitial Pulmonary Infiltrates

A man with HIV had syncopal episodes and hypoxemia after recent exposure to SARS-CoV-2; computed tomography revealed diffuse bilateral pulmonary micronodular opacities, a 2.2-cm nodule in the lingula, and mediastinal and hilar lymphadenopathy. What is the diagnosis and what would…

Diagnosis and Management of Aortic Diseases

This JAMA Clinical Guidelines Synopsis summarizes the 2022 American College of Cardiology/American Heart Association guidelines for diagnosis and management of aortic disease.

Collaborative Modeling to Compare Different Breast Cancer Screening Strategies – A Decision Analysis for the US Preventive Services Task Force

Importance  The effects of breast cancer incidence changes and advances in screening and treatment on outcomes of different screening strategies are not well known. Objective  To estimate outcomes of various mammography screening strategies. Design, Setting, and Population  Comparison of outcomes using 6 Cancer…