JAMA

Diffuse Cutaneous Eruption

A man presented with a pruritic cutaneous eruption that began on his scalp and face and over 2 months spread across most of his body. Physical examination revealed confluent salmon-colored plaques with areas of unaffected skin; waxy, exfoliative scale on…

Extracorporeal Cardiopulmonary Resuscitation for Cardiac Arrest

This JAMA Insights Clinical Update discusses the newer treatment option of extracorporeal cardiopulmonary resuscitation, particularly for patients with cardiac arrest who are not responsive to initial treatment.

Prescribing Opioids for Pain

This JAMA Clinical Guidelines Synopsis summarizes the Centers for Disease Control and Prevention’s 2022 clinical practice guideline for prescribing opioids for pain.

Abdominal Pain and Hypotension in a 70-Year-Old Woman

A 70-year-old woman with hypertension, atrial fibrillation, congestive heart failure, and gallstones had 3 days of nausea, vomiting, and abdominal pain. Abdominal computed tomography showed a thickened gallbladder wall with intraluminal air adherent to the duodenum and a gallstone in…

Abdominal Pain and Petechial Rash in a 95-Year-Old Farmer

A 95-year-old farmer taking prednisolone for bullous pemphigoid had 24 hours of abdominal pain, 2 weeks of diarrhea, and 3 months of intermittent abdominal bloating and anorexia. Evaluation showed purpuric macules and small thumbprint-like patches on her upper abdomen and…

Creation and Adoption of Large Language Models in Medicine

Importance  There is increased interest in and potential benefits from using large language models (LLMs) in medicine. However, by simply wondering how the LLMs and the applications powered by them will reshape medicine instead of getting actively involved, the agency in…

Patents and Regulatory Exclusivities on GLP-1 Receptor Agonists

Importance  Glucagon-like peptide 1 (GLP-1) receptor agonists were first approved for the treatment of type 2 diabetes in 2005. Demand for these drugs has increased rapidly in recent years, as indications have expanded, but they remain expensive. Objective  To analyze how manufacturers…

Cervical Cancer Screening – A Review

Importance  Each year in the US, approximately 100 000 people are treated for cervical precancer, 14 000 people are diagnosed with cervical cancer, and 4000 die of cervical cancer. Observations  Essentially all cervical cancers worldwide are caused by persistent infections with one of 13…