Medical Knowledge

Viral Meningoencephalitis and Bilateral Blurry Vision

A 20-year-old Chinese woman was experiencing fever, malaise, headache, nausea, vomiting, and neck stiffness for 2 weeks. Further examination revealed inflammation, vitritis and cystoid macular edema, tortuous dilatation of retinal venous vessels with fluorescence leakage, and hyperfluorescence in the optic…

Advancing Global Pharmacoequity in Oncology

Importance  Limited availability and affordability of cancer drugs contribute to staggering disparities in cancer survival between high-income and low- and middle-income countries (LMICs). As infrastructure for cancer care rapidly develops, there is an urgent need to reduce prices and improve access…

Management of Atrial Fibrillation

This JAMA Clinical Guidelines Synopsis summarizes the 2023 ACC/AHA/ACCP/HRS guideline for the diagnosis and management of atrial fibrillation.

Clinical Presentation, Investigation Findings, and Outcomes of IgG4-Related Pachymeningitis – A Systematic Review

Importance  Immunoglobulin G4 (IgG4)–related disease is an increasingly recognized fibroinflammatory condition that can involve multiple organs, including the pachymeninges. The understanding of IgG4-related pachymeningitis (IgG4-RP) remains limited because of its rarity and the predominance of knowledge derived from case reports and…

Diagnosis and Treatment of Polycythemia – A Review

Importance  Polycythemia vera (PV), a myeloproliferative neoplasm characterized by an increased red blood cell mass and increased risk of thrombosis, affects approximately 65 000 people in the US, with an annual incidence of 0.5 to 4.0 cases per 100 000 persons. Observations  Erythrocytosis (hemoglobin…

NCCN Guidelines in PractiCE

To provide optimal patient care, clinicians need to be well informed about the latest clinical research updates and how these advances compare to the current clinical practice standards. This activity will allow for self-directed online learning to assist in the…

Admissions After Ambulatory Surgery

Ambulatory surgery is growing in popularity among physicians and patients. While it can be convenient and less expensive, ambulatory surgery also has risks. The risks oblige all those involved with ambulatory surgeries to make effective decisions about what procedures to…

Diagnostic Safety, Part 5: Systems Factors

This activity discusses ways systems factors (flaws or weaknesses in organizational systems of care) can sabotage correct diagnoses. Think about a primary care practice with no specific policy for checking if patients actually go to recommended tests and consults, which…

Diagnostic Safety, Part 4: The Value of the Differential Diagnosis

In medicine, the formulation of a differential diagnosis is fundamental to the diagnostic reasoning process. It is less likely to find documentation of a differential diagnosis in cases that have diagnostic errors. This activity presents strategies to fortify the differential…