Medical Knowledge

Trauma-Informed Care

This JAMA Insights discusses trauma-informed care practices that can help clinicians provide sensitive and supportive care that may improve health outcomes in patients with a history of trauma.

A New Dystonia Phenotype in Wilson Disease

This case report describes a 36-year-old male patient with Wilson disease and opposite muscle tone manifestations in his upper and lower limbs.

Intrapartum Sildenafil to Improve Perinatal Outcomes – A Randomized Clinical Trial

Importance  Sildenafil citrate may increase uteroplacental blood flow. Its ability to reduce perinatal complications related to fetal hypoxia during labor is uncertain. Objective  To compare the effectiveness of intrapartum maternal oral sildenafil citrate vs placebo in improving perinatal outcomes potentially related to…

Safer Prescribing of Opioids for Pain Management

As health care professionals, it is essential to prescribe opioids safely and appropriately to ensure effective and equitable pain management while minimizing risk. This course offers an overview and application of safer opioid prescribing practices through five patient interactions in…

AMA STEPSFORWARD – Johns Hopkins: An AI Success Story

Dr Alvin Liu, an endowed professor of the AI Oversight Team and inaugural director of the James P. Gills Jr., MD, & Heather Gills Artificial Intelligence Innovation Center at Johns Hopkins Medicine, discusses Johns Hopkins Medicine’s journey with Augmented Intelligence…

Patent Foramen Ovale and Dysarthria in a Man in His 60s

This case report describes a diagnosis of patent foramen ovale in a man in his 60s presenting with stroke symptoms and multifocal infarcts on magnetic resonance imaging of the brain.

Augmented Enteral Protein During Critical Illness – The TARGET Protein Randomized Clinical Trial

Importance  Guidelines recommend augmenting enteral protein during critical illness, but the impact on patient outcomes is uncertain. Objective  To determine whether augmenting enteral protein increases days alive and free from hospitalization. Design, Setting, and Participants  This cluster randomized, crossover, open-label trial recruited critically…

Rescheduling Cannabis—Medicine or Politics?

Importance  In 2023, the US Department of Health and Human Services (HHS) issued a letter to the administrator of the Drug Enforcement Administration (DEA) recommending rescheduling of cannabis (marijuana) from Schedule I to Schedule III under the Controlled Substances Act (CSA)….