Medical Knowledge

PostñIntensive Care Syndrome

This JAMA Insights discusses postñintensive care unit syndrome, including how it is assessed and diagnosed as well as suggestions for treatment and prevention.

Evaluation of the Validity of International Classification of Diseases Codes for Dermatologic Conditions A Systematic Review

  Importance  Accurate classification of dermatologic conditions using International Classification of Diseases (ICD) codes is essential for research that uses large administrative datasets. Misclassification can be associated with biased epidemiologic estimates and misleading conclusions in population-based studies. Objective  To systematically identify and evaluate validated…

Sibling Comparisons to Account for Confounding in Observational Studies

This JAMA Guide to Statistics and Methods explains how sibling analysis can be used to account for confounding in observational studies, using the example of a study on acid suppressants during pregnancy and risk of neuropsychiatric disorders in offspring.

Generalized Atrophic Papules and Acute Abdominal Pain

An adolescent female presented with 3 days of progressive abdominal pain and reported that a rash first appeared nearly 1 year earlier on her left wrist and gradually spread over several weeks. What is your diagnosis?

Exertional Syncope in a Female Teenage Student

A previously healthy female teenager presents with chest tightness and syncope after exertion. Electrocardiogram results showed ST-segment elevation in leads V1 through V4, aVL, and aVR, and laboratory results indicated elevated cardiac troponin T levels. What would you do next?

Unmasking a Masquerade of Ocular Dysgenesis

A 66-year-old man had nebulomacular corneal opacities, iris atrophy, and corectopia along with coarse facial skin, resorbed digits, anesthetic patches, and healed trophic skin ulcers. What would you do next?

Stillbirth

This JAMA Insights focuses on stillbirth, including causes, risk factors, and prenatal preventive care.

Ten Core Concepts for Ensuring Data Equity in Public Health

Importance  Public health decisions increasingly rely on large-scale data and emerging technologies such as artificial intelligence and mobile health. However, many populations—including those in rural areas, with disabilities, experiencing homelessness, or living in low- and middle-income regions of the world—remain underrepresented…