Dental Caries in Adults
This JAMA Insights discusses the causes and treatment of dental caries in US adults as well as preventive measures for patients and medical and dental clinicians.
Medical Knowledge
A 13-Year-Old Male With Parotid Region Mass
A 13-year-old male presented with a 7-month history of a painless, progressively enlarging mass in the right parotid region. What is your diagnosis?
Large Choroidal Excavation in Stargardt Disease
This case report describes a large choroidal excavation and outer retinal atrophy in an otherwise healthy man aged 29 years who presented with bilateral gradually worsening vision since childhood.
National Alliance of Sickle Cell Centers Consensus Recommendations on Sickle Cell Disease Health Maintenance – A Consensus Statement
Importance The most common inherited blood disorder in the world, sickle cell disease (SCD) is a known global health concern. While survival of children into adulthood has improved significantly over the last few decades in high-resource countries, substantial gaps in care…
Deep Learning in Otolaryngology – A Narrative Review
Importance Deep learning (DL), a subset of artificial intelligence, uses multilayered neural networks to uncover complex patterns in large datasets without manual feature engineering. Unlike traditional machine learning, DL autonomously learns hierarchical representations from raw data, offering distinct advantages for analyzing…
Immune Checkpoint Inhibitor–Associated Cardiovascular Toxic Effects – International Cardio-Oncology Society Position Statement
Importance The introduction of immune checkpoint inhibitor (ICI) therapy has improved cancer outcomes but at the cost of adverse events, mainly related to the immune system. Cardiovascular (CV) toxic effects, and especially myocarditis, are of particular concern and are the subject…
US Laws Restricting Medical Care for Transgender Minors – Statutory Inconsistencies Involving Intersex and Other Individuals
Importance Since 2021, there have been growing calls in the US to prohibit gender-affirming medical care (GAMC) for transgender and gender-diverse (TGD) minors (ie, <18 years). Supporters of these bans have argued the restrictions are necessary to protect TGD minors from…
Implementing Benzodiazepine Deprescribing in the Primary Care Clinic
This Clinical Insight contextualizes benzodiazepine deprescribing guidelines for primary care physicians and high-risk populations.
Arsenic Exposure Reduction and Chronic Disease Mortality
Importance Chronic exposure to arsenic in drinking water has been associated with increased chronic disease mortality. However, there is limited evidence on associations between reduced exposure and mortality risk. Objective To examine whether reductions in arsenic exposure, measured using urinary arsenic levels,…
Peripheral Neuropathy – A Review
Importance Peripheral neuropathy, defined as damage to peripheral nerves, affects approximately 1% of adults worldwide. More than 200 causes of peripheral neuropathy exist, with symptoms ranging in severity from mild toe numbness to debilitating symptoms that can require a wheelchair. Diabetes…
