Importance Psilocybin use has surged in the US following decriminalization efforts and promising clinical trial results. Mirroring early cannabis legalization, public access and enthusiasm are outpacing regulatory oversight and scientific understanding, posing potential risks to public health. Objective To review emerging evidence…
A healthy 25-year-old female presented with an 8-month history of a painful right mandibular lesion. What is your diagnosis?
A previously healthy 31-year-old woman presents with acute unilateral anterior uveitis with hypopyon and an iris lesion and systemic symptoms, including headache, fatigue, and fever. What would you do next?
Importance Acute myeloid leukemia (AML) is a severe hematologic cancer with complex genetic heterogeneity necessitating personalized treatment approaches. Artificial intelligence (AI) technologies may revolutionize risk stratification, diagnosis enhancement, and treatment planning in addressing critical gaps in AML management, particularly in low-resource…
Importance Persons with heterozygous familial hypercholesterolemia (HeFH) are at increased risk of atherosclerotic cardiovascular disease due to lifelong elevated levels of low-density lipoprotein cholesterol (LDL-C). Many patients with HeFH do not achieve guideline-recommended LDL-C goals with the currently available lipid-lowering therapies….
Importance Risk stratification strategies in primary prevention of coronary events lack precision. Objective To determine whether prediction of first coronary events is improved by adding information on coronary atherosclerosis from coronary computed tomography angiography (CCTA) to a model using the pooled cohort…
Importance Conventional wisdom holds that caffeinated coffee is proarrhythmic. Coffee is the most commonly consumed caffeinated beverage in the US, and a randomized trial assessing caffeinated coffee consumption in patients with atrial fibrillation (AF) has not previously been performed. Objective To determine…
Importance The Dietary Approaches to Stop Hypertension (DASH) eating plan lowered blood pressure (BP) among Black adults in a controlled environment, but to date, there are no grocery shopping strategies that replicated its health effects in a community setting. Objective The Groceries…
This case report describes a patient with left-sided weakness following transient ischemic attacks who underwent external carotid angioplasty based on findings from ultrahigh-resolution photon-counting computed tomographic angiography (CTA).
This JAMA Insights discusses the clinical presentation, diagnosis, and treatment of primary biliary cholangitis.
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