As health care professionals, it is essential to prescribe opioids safely and appropriately to ensure effective and equitable pain management while minimizing risk. This course offers an overview and application of safer opioid prescribing practices through five patient interactions in…
Dr Alvin Liu, an endowed professor of the AI Oversight Team and inaugural director of the James P. Gills Jr., MD, & Heather Gills Artificial Intelligence Innovation Center at Johns Hopkins Medicine, discusses Johns Hopkins Medicine’s journey with Augmented Intelligence…
This case report describes a woman in her 60s with hypertrophy of dorsal tongue papillae in a honeycomb pattern along with papillomatous growth of the gingiva.
A man in his early 50s presented with recurrent episodes of cough, palpitations, shortness of breath, and exertional chest pain. What would you do next?
This case report describes a diagnosis of patent foramen ovale in a man in his 60s presenting with stroke symptoms and multifocal infarcts on magnetic resonance imaging of the brain.
Importance Guidelines recommend augmenting enteral protein during critical illness, but the impact on patient outcomes is uncertain. Objective To determine whether augmenting enteral protein increases days alive and free from hospitalization. Design, Setting, and Participants This cluster randomized, crossover, open-label trial recruited critically…
Importance In 2023, the US Department of Health and Human Services (HHS) issued a letter to the administrator of the Drug Enforcement Administration (DEA) recommending rescheduling of cannabis (marijuana) from Schedule I to Schedule III under the Controlled Substances Act (CSA)….
This JAMA Guide to Statistics and Methods explains tipping point analysis, which assesses how a range of hypothetical patterns in missing outcome data in a randomized clinical trial (RCT) would affect the study’s conclusions, and examines its use in an…
Importance Adrenal insufficiency is a syndrome of cortisol deficiency and is categorized as primary, secondary, or glucocorticoid induced. Although primary and secondary adrenal insufficiency are rare, affecting less than 279 per 1 million individuals, glucocorticoid-induced adrenal insufficiency is common. Observations Primary adrenal…
Importance The US Food and Drug Administration (FDA) and National Institutes of Health (NIH) share a mutual interest in facilitating efficient, well-designed clinical studies of drugs, devices, and biological products. Recent advances in science and technology, as well as innovative approaches…
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