Alkaptonuria
This case report describes a man in his 50s with progressive blue-gray discoloration of sun-exposed areas, including the nose, cheeks, ears, and hands.
ABMS Lifelong Learning CME Activity
Dry EEG—From Laboratory to Living Room
This article discusses the potential applications of dry electroencephalography (EEG) and its advantages over traditional wet EEG.
Add-On Treatment With Zilebesiran for Inadequately Controlled Hypertension – The KARDIA-2 Randomized Clinical Trial
Importance In prior monotherapy studies of patients with hypertension, single subcutaneous doses of zilebesiran, an investigational RNA interference therapeutic, reduced serum angiotensinogen levels and systolic blood pressure (SBP) at 3 and 6 months. Objective To evaluate the efficacy and safety of zilebesiran…
Uveitis in Adults – A Review
Importance Uveitis is characterized by inflammation of the uvea—the middle portion of the eye composed of the iris, ciliary body, and choroid—causing eye redness, pain, photophobia, floaters, and blurred vision. Untreated uveitis may cause cataracts, glaucoma, macular edema, retinal detachment, optic…
Tracheobronchial Replacement – A Systematic Review
Importance Tracheobronchial replacement remains a surgical and biological challenge despite several decades of experimental and clinical research. Objective To compile a comprehensive state-of-the-science review examining the current indications, techniques, and outcomes of tracheobronchial replacement in human patients. Evidence Review A systematic review of…
Oral Mass in an Infant
A 39-week-old female infant had a large oral mass at delivery and had difficulty feeding without notable respiratory distress. What is your diagnosis?
A Woman With Headache, Fatigue, and Aphasia
A woman with no significant medical history had 3 days of headache, fatigue, and expressive aphasia; laboratory testing showed microangiopathic hemolytic anemia, increasing schistocytes on serial blood smears, diminished ADAMTS13 activity, and a high inhibitor titer. What is the diagnosis…
Platelet Transfusion – 2025 AABB and ICTMG International Clinical Practice Guidelines
Importance Platelet transfusion is a frequent procedure with benefits and risks. Objective To provide recommendations in adult and pediatric populations in whom platelet transfusions are commonly performed. Evidence Review Grading of Recommendations Assessment Development and Evaluation (GRADE) methodology was applied to findings from…
Ethics Talk: Whose Bodies Should Be Represented in Art?
This activity is comprised of five multiple-choice questions based on the content of an AMA Journal of Ethics podcast about what clinicians and other health professionals should know about embodiment. The featured guest is Christine Slobogin, PhD an assistant professor…
Psychogeography as Embodied Connection to Place
This article introduces psychogeography as a research method that relies on embodied practices of drifting (dÈrive) through a city, which are followed by subsequent creative cartography. Mapping and documentation that follow dÈrive promote fuller understanding of persons’ patterns of embodying…
