Geyserlike OCT Sign in Transthyretin Amyloidosis
This case report discusses a diagnosis of transthyretin amyloidosis after an unusual finding on optical coherence tomography (OCT) in a woman aged 52 years with dense vitreous opacities.
ABMS Lifelong Learning CME Activity
Adult Male Hypogonadism – A Review
Male hypogonadism is a clinical syndrome of signs and symptoms of testosterone deficiency and consistently low morning serum testosterone concentrations. The prevalence of hypogonadism due to hypothalamus, pituitary, or testes pathology is less than 1%, and the prevalence due to…
Circulating Tumor DNA in Early Breast Cancer – A Review
Circulating tumor DNA (ctDNA) has emerged as a noninvasive biomarker with the potential to detect minimal residual disease (MRD), monitor treatment response, and identify recurrence (eg, molecular relapse) earlier than conventional clinical or imaging approaches. Although ctDNA-based MRD assays have…
The Role of AI in Medical Education
AI (artificial and augmented intelligence) is playing an increasingly important role at all stages of the medical education continuum, both as a tool for educators and learners. In this episode Catalyzing Change in MedEd, host Kim Lomis*, MD, VP, Innovations…
Diffuse Pruritic Maculopapular Rash With Pitted Necrosis
A previously healthy woman in her 30s presented with a diffuse maculopapular rash, most prominently on her legs, with pitted necrotic spots, black eschar, and serous fluid weeping with diffuse edema. Histopathology showed areas with abnormal aggregates composed almost entirely…
Pancreatic Panniculitis in a Patient With Lung Cancer
This case report describes a woman in her 50s with metastatic lung adenocarcinoma who presented with a 4-week history of severe arthralgias and painful nodules on her skin.
Hearing Aids for Adults With Mild to Moderate Hearing Loss
This JAMA Insights discusses hearing aids for adults with mild to moderate hearing loss, including hearing aid function and limitations and prescription vs over-the-counter hearing aid devices.
Strategies for Establishing Clinical-Decision Thresholds in Psychiatry – A Review
Importance Nearly all psychopathology is inherently continuous, but both clinical practice and research often require categorical decisions (eg, treat or wait, pay for treatment or decline, enroll in study or not); therefore, thresholds are applied to continuous phenomena to guide…
Aberrant Left-to-Right Fusion of the Oculomotor Nerve
This case report describes a 2-year-old girl with congenital ptosis of the left eye, large-angle exotropia, adduction deficit of the left eye, and abduction deficit of the right eye.
A Low-Voltage Electrocardiogram
This case report describes a woman in her 60s who had an inferior wall myocardial infarction 1 year prior and presented to the emergency department with worsening dyspnea and anasarca for the past 2 months.
