Approach to Scarring Alopecia
This Clinical Insights outlines the clinical characteristics, diagnostic approach, and therapeutic strategies for managing scarring alopecias.
ABMS Lifelong Learning CME Activity
Ethics Talk: Why Has US Health Research Shifted From Social and Environmental Factors to Genetics?
This activity is comprised of five multiple-choice questions based on the content of an AMA Journal of Ethics podcast about how US health research has shifted from social and environmental factors to genetics over the course of the mid-to-late 20th…
What Should Be Roles of Industry and the Public in Diagnostic Research?
Despite legislative attention from Congress in the 1980s, diagnostic research on rare diseases is not lucrative enough to garner sufficient private funding. The Undiagnosed Diseases Network supports diagnostic research and intervention innovation for patients with undiagnosed or rare conditions. This…
What Matters Ethically About How the UDN Has Changed Since Its Inception?
For persons living with an undiagnosed disease and their families, finding an accurate diagnosis can be a long and complex process. Having a rare condition that goes undiagnosed for a long period constitutes a significant part of these patients’ disease…
What Are Ethical Merits and Drawbacks of Viewing “Medical Mysteries” as Human Subject Research?
Patient-subjects’ participation in an Undiagnosed Diseases Network (UDN) protocol can afford access to innovative diagnostic techniques, especially in genomic medicine, which can shorten the time it takes to accurately diagnose a so-called “medical mystery.” But UDN research processes can be…
Management of Severe Refractory Asthma
This JAMA Insights explores the management of severe refractory asthma, including medications, access to specialists, and managing environmental triggers.
Is the UDN N-of-1 Enterprise Ethically Justifiable?
The Undiagnosed Diseases Network is a national consortium of clinicians and researchers working to promote diagnostic research and accurately diagnose patients with rare diseases, many of whose conditions have long gone undiagnosed. This endeavor’s importance should not, however, stop us…
How Should Students and Trainees Be Taught to Support Patients With Undiagnosed Conditions?
Patients with undiagnosed conditions often experience frustration and lose trust in health care. This article suggests how faculty in academic health centers can prepare their students and trainees to respond with care to the vulnerabilities and needs of patients seeking…
Bariatric Surgery, Employment, and Productivity Outcomes – A Systematic Review
Importance Bariatric surgery is widely recognized for its health benefits; however, its association with work productivity and employment participation, though frequently reported, has not been systematically synthesized. This evidence is crucial to inform the economic evaluation of bariatric surgery. Objective To systematically…
Head and Neck Cancer Salvage Surgery in the Era of Immunotherapy and Beyond – A Review
Importance Head and neck squamous cell carcinoma (HNSCC) is a challenging malignant condition associated with significant morbidity and mortality. Salvage surgery, in addition to other available treatment modalities, constitutes an important therapeutic intervention for locoregionally recurrent HNSCC, offering the potential for…
