Journal-based

Lateral Neck Bulging and Pain on Swallowing in a Young Man

A 28-year-old man presents with a bulge on the left side of his neck and severe stabbing pain during swallowing. He had a history of a neck contusion 1 year prior with subcutaneous bleeding that had improved. What is your…

A 3-Year-Old With Gingival Hemorrhage and Musculoskeletal Pain

A 3-year-old had spontaneous gingival hemorrhage and bilateral limb weakness with inability to bear weight. He had no preceding oral trauma or recent infection, took no regular medications, and had no recent use of aspirin or nonsteroidal anti-inflammatory drugs; his…

Opioid-Induced Adrenal Insufficiency

This case report describes a woman in her 40s with opioid use disorder receiving methadone who was admitted for extended antibiotic treatment for methicillin-resistant Staphylococcus aureus bacteremia and was subsequently diagnosed with opioid-induced adrenal insufficiency.

Acute Corneal Edema in a Middle-Aged Patient

A middle-aged patient who had bilateral penetrating keratoplasty 20 years ago for keratoconus presented with pain and blurriness of the right eye for 2 days. Despite prompt corticosteroid therapy, they had no vision improvement and reported occasional pain. What would…

Climate Change and Mental Health

This JAMA Insights discusses the adverse effects of climate change on mental health and proposes solutions to help mitigate those effects.

Survival Benefit Associated With Participation in Clinical Trials of Anticancer Drugs – A Systematic Review and Meta-Analysis

Importance  Many cancer clinical investigators view clinical trials as offering better care for patients than routine clinical care. However, definitive evidence of clinical benefit from trial participation (hereafter referred to as the participation effect) has yet to emerge. Objective  To conduct a systematic…

Krill Oil for Knee Osteoarthritis – A Randomized Clinical Trial

Importance  Knee osteoarthritis is disabling, with few effective treatments. Preliminary evidence suggested that krill oil supplementation improved knee pain, but effects on knee osteoarthritis remain unclear. Objective  To evaluate efficacy of krill oil supplementation, compared with placebo, on knee pain in people…

Federal Trade Commission Actions on Prescription Drugs, 2000-2022

Importance  The Federal Trade Commission’s (FTC) oversight role in the pharmaceutical market is critical to the health of patients and the health care system. This study characterized the FTC’s policy on the pharmaceutical market in recent decades, identifying the types of…