Design is and always has been interventional and clinically relevant. Modern evidence-based designers’ lineage was prominently shaped between 1800 and 1970. This article investigates hospital designs during this period that were correlated with patients’ health outcomes and suggests how this…
This case report describes a man in his 60s with hypertension, deep vein thrombosis, and a recent diagnosis of HIV presented with low CD4 cell count after starting antiretroviral therapy with tenofovir alafenamide-emtricitabine-bictegravir.
A man in his early 50s presented to autoimmune dermatology clinic for 3 years of periarticular nodules on his fingers that were painful with manipulation or minor trauma and symmetric polyarthralgia. What is your diagnosis?
This case report describes a man in his 50s with palmar fasciitis and polyarthritis syndrome.
Importance Axial spondyloarthritis is an immune-mediated inflammatory condition involving the sacroiliac joints, spine, and peripheral joints. It affects approximately 1% of adults in the US and is associated with impaired physical function and reduced quality of life. Observations Inflammatory chronic back pain…
Importance In poor-prognosis children’s cancers, new therapies may carry fresh hope for patients and parents. However, there is an absolute requirement for any new therapy to be properly evaluated to fulfill scientific, regulatory, and reimbursement requirements. Randomized clinical trials (RCTs) are…
This Clinical Insights discusses how the methicillin-resistant Staphylococcus aureus (MRSA) nares swab may be used alongside disease prevalence and clinical factors to determine when MRSA coverage is needed for common inpatient infections.
This JAMA Insights discusses allogenic stem cell donation, including the donation process and the effects of stem cell donation on donors.
A 75-year-old woman with a history of essential thrombocythemia presented with 3 months of progressively enlarging right upper eyelid lesions. Examination revealed a thickened eyelid margin, madarosis, and erythema with some tenderness to palpation but an otherwise normal ocular examination….
Importance The commercialization of chimeric antigen receptor–T-cell (CAR-T) therapy has changed the landscape of treatment of hematological cancers. Numerous studies from the early 2000s paved the way for cell-based targeted therapeutics, which have been established as practice-changing therapies in lymphoma, leukemia,…
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