JAMA Ophthalmology

A Case of a Bumpy Retina

A 77-year-old male had 3 months of progressive vision decline in the left eye. Dilated fundus examination revealed diffuse hyperpigmented lesions involving the macula and superior fundus that corresponded to areas of nodular retinal pigment epithelium thickening on optical coherence…

A Suspicious Pigmented Lesion of the Conjunctiva

A 74-year-old woman with a history of breast cancer, now in remission, presented for evaluation of a conjunctival lesion of the right eye. What would you do next?

Maculopathy in a 52-Year-Old Patient With Diabetes

A 52-year-old woman with severe nonproliferative diabetic retinopathy had decreased vision and macular edema in both eyes that was not responding to treatment. What would you do next?

Posterior Segment Changes in Gaucher Disease

This case report discusses posterior segment characteristics in a patient aged 24 years with low vision and a history of Gaucher disease.

Bilateral Blurry Vision After a Liver Transplant

A 31-year-old woman presented for evaluation of bilateral blurry vision over the past month. She experienced fulminant hepatic failure 3 months ago and underwent a liver transplant 2 weeks later. Postoperative pathological results showed hepatolenticular degeneration. What would you do…

Cystic-Appearing Eyelid Lesion in a 62-Year-Old Man

A 62-year-old male was referred for evaluation of a painless right lower-eyelid lesion noted during routine glaucoma follow-up. The lesion had been present for 3 years with slow, gradual enlargement. What would you do next?

An Atypical Optic Nerve Head Mass

A 47-year-old man presented with a sudden decrease in vision in the right eye and a history of binocular diplopia, bilateral cranial nerve 6 palsies, and an undifferentiated pontine mass. Examination revealed a large optic nerve head mass with optic…