JAMA Ophthalmology

Red Eyes Refractory to Corticosteroids

A 57-year-old man with bilateral red eyes and irritation refractory to topical corticosteroids presents with symmetric yellow conjunctival lesions and progressive systemic nodules and joint pain. What would you do next?

CNV and Angioid Streaks in Pseudoxanthoma Elasticum

This case report discusses a diagnosis of pseudoxanthoma elasticum in a woman aged 47 years who presented with bilateral blurry vision and a history of intravitreal treatment for choroidal neovascularization (CNV).

Geyserlike OCT Sign in Transthyretin Amyloidosis

This case report discusses a diagnosis of transthyretin amyloidosis after an unusual finding on optical coherence tomography (OCT) in a woman aged 52 years with dense vitreous opacities.

Optic Disc and Macular Edema in a Previously Healthy Teenager

A 16-year-old female presents to your clinic with 5 weeks of blurry vision in the left eye, headaches, weight loss, fevers, chills, night sweats, fatigue, generalized weakness, dizziness, chest pain, and shortness of breath. What would you do next?

Intralenticular Stratification in a Complicated Cataract

This case report discusses intralenticular stratification in the cataract of a boy aged 13 years with a history of familial exudative vitreoretinopathy and total retinal detachment.

Blunt Ocular Trauma in a 6-Year-Old Child

This case report describes the ocular injury incurred after blunt ocular trauma secondary to a fishhook in the left eye of a male child, aged 6 years.

Web-Based Amblyopia Decision Support Tool

Importance  Amblyopia is the leading cause of monocular decreased best-corrected vision in children. Early detection and intervention are key for optimal treatment outcomes; however, limited access to pediatric eye specialists may hinder timely care and affect visual outcomes. Given the…

Ophthalmoplegia and Ptosis After Cancer Immunotherapy

An 82-year-old man presented with 4 months of fluctuating diagonal binocular diplopia and progressive bilateral ptosis. Examination in the strabismus clinic revealed variable ptosis and ophthalmoplegia in multiple gaze directions, with a large-angle esotropia and left hypotropia. What would you…