JAMA Ophthalmology

AS-OCT Imaging of River Water Granuloma in a Child

This case report discusses a diagnosis of trematode granuloma in a child aged 8 years who presented with a painful red right eye after 2 weeks of river swimming.

Outer Retinal Disruption in a Young Male

A 17-year-old male with a 3-month history of bilateral blurred vision and photophobia presents with placoid lesions in both eyes and further vision loss in the right eye. What would you do next?

Vitreous Opacities and Polyneuropathy in a 38-Year-Old Woman

A 38-year-old woman presented with eye heaviness and mild blurred vision without pain, illness, or trauma and a history of chronic inflammatory demyelinating polyneuropathy, unintentional weight loss, and gastrointestinal symptoms. Examination revealed bilateral vitreo-arterial tufts and scattered vitreous hyper-reflective signal…

Hemorrhagic Occlusive Retinal Vasculitis and Intravitreal Anti-VEGF

This case report discusses bilateral vision loss 2 weeks after second bilateral intravitreal injection of the antiñvascular endothelial growth factor (VEGF) brolucizumab for diabetic macular edema in a woman in her 60s.

Atypical Presentation of Conjunctival Kaposi Sarcoma

This case report discusses a diagnosis of conjunctival Kaposi sarcoma in a male patient aged 26 years with a history of advanced HIV infection who presented with a painless red conjunctival nodule.

Subretinal Fluid and Optic Disc Edema in a Healthy Adult

A 42-year-old man had a 1-year history of painless blurred vision and visual field defect in the right eye that had acutely worsened over the past month, and he reported headache and neck stiffness. What would you do next?