JAMA Ophthalmology

Subconjunctival Mass 30 Years After Melanoma Resection

A 70-year-old male is referred for evaluation of a conjunctival mass in the right eye, which has grown slowly over 27 years. Examination reveals a superonasal, multilobulated, pigmented lesion with episcleral feeder vessels and spontaneous vascular pulsations within the intraocular…

Branch Retinal Artery Occlusion in an Adolescent Male

A 17-year-old male with an unremarkable medical history presented with 2 days of painless blurred vision in the right eye. Three weeks prior, he was admitted with fever, myalgias, hepatosplenomegaly, lymphadenopathy, and truncal rash. What would you do next?

Bilateral Perifoveal Atrophy in a 46-Year-Old Woman

A 46-year-old woman is referred for a second opinion with recent onset of suspected seizures and imbalance. Fundus examination revealed bilateral discrete perifoveal circular areas of atrophy. What would you do next?

Viral Meningoencephalitis and Bilateral Blurry Vision

A 20-year-old Chinese woman was experiencing fever, malaise, headache, nausea, vomiting, and neck stiffness for 2 weeks. Further examination revealed inflammation, vitritis and cystoid macular edema, tortuous dilatation of retinal venous vessels with fluorescence leakage, and hyperfluorescence in the optic…

Skin Discoloration After Iatrogenic Fluorescein Dosing Error

This case report describes a diagnosis of iatrogenic fluorescein dosing error in a girl aged 10 months who presented for routine fluorescein angiography examination in the setting of incontinentia pigmenti.

Retinopathy After Epiretinal Membrane Peeling

This case report describes a diagnosis of maculopathy associated with mechanical trauma from epiretinal membrane peeling in a man aged 84 years.

Looking Beyond and Behind a Retinal Detachment

A 63-year-old woman with a history of type 1 diabetes presents with gradually progressive vision loss in the right eye for the past year. What would you do next?

Progressive Eyelid Lesions in a Woman With Essential Thrombocythemia

A 75-year-old woman with a history of essential thrombocythemia presented with 3 months of progressively enlarging right upper eyelid lesions. Examination revealed a thickened eyelid margin, madarosis, and erythema with some tenderness to palpation but an otherwise normal ocular examination….

Bilateral Retinal Nerve Fiber Layer Thickening in a Middle-Aged Woman

A middle-aged Hispanic woman presented for evaluation of an asymptomatic epiretinal membrane in the left eye. She had an ocular history of amblyopia in the left eye, a medical history significant for chronic neuropathy, ataxia, and myelopathy of unknown etiology,…