JAMA Network Open

Advancing Health Disparities Science Through Social Epigenomics Research

Importance  Although scientific and technological discoveries have improved the health of the US population overall, racial and ethnic minority (American Indian and Alaska Native, Asian, Black or African American, Hispanic or Latino, or Native Hawaiian and Pacific Islander persons) and socioeconomically…

Enhancing Postmarketing Surveillance of Medical Products With Large Language Models

Importance  The Sentinel System is a key component of the US Food and Drug Administration (FDA) postmarketing safety surveillance commitment and uses clinical health care data to conduct analyses to inform drug labeling and safety communications, FDA advisory committee meetings, and…

The Key Features of a Genetic Nondiscrimination Policy – A Delphi Consensus Statement

Importance  Governments worldwide have become increasingly cognizant of the spread of genetic discrimination (negative treatment or harm on the basis of actual or presumed genetic characteristics). Despite efforts by a number of governments to establish regulations addressing this phenomenon, public concern…