Importance Urinary tract infection (UTI) is common in ambulatory care settings and the primary reason for antibiotic prescribing. Despite several guidelines focused on the type and duration of antibiotics prescribed for treating UTI, there is limited outpatient guidance on how to…
Importance Antimicrobial resistance (AMR) poses an urgent global health challenge, undermining treatment efficacy and threatening patient safety. Antimicrobial stewardship (AMS) programs are recognized as essential interventions to optimize antibiotic use, but implementation has often been fragmented and underresourced. The Republic of…
Importance The Latina, Latino, Latinx, Latine, Hispanic, or of Spanish Origin (LHS+) population is 20% of the US population and experiences disparities in health care access and quality. The common mission of medical schools is to prepare future health care practitioners…
Importance The emergence of fentanyl in the setting of the US opioid crisis demands reconsideration of clinical approaches to buprenorphine initiation for patients with opioid use disorder (OUD), with the rationale that fentanyl’s unique pharmacology leads to a greater risk of…
Importance Immunocompromised individuals are a large and growing population who are at increased risk for infectious diseases. There has and continues to be a lack of focus on clinical trials to establish the safety and efficacy of therapies for infectious diseases…
Importance Observational studies can provide valuable insights to inform decisions on health equity. Existing guidelines for reporting such studies, such as the Strengthening the Reporting of Observational Studies in Epidemiology (STROBE) statement, currently lack specific considerations for reporting on health equity….
Importance The role of pesticide exposure from golf courses in Parkinson disease (PD) risk remains unclear. Objective To assess whether proximity to golf courses is associated with increased PD risk and to use information on groundwater vulnerability and municipal well locations to…
Importance Many adolescents and young adults (AYAs) in low- and middle-income countries (LMICs) are excluded from HIV research because of challenges with informed consent for study participation, which makes it difficult to understand and improve the lives of AYAs living with…
Importance The US Food and Drug Administration (FDA) and National Institutes of Health (NIH) share a mutual interest in facilitating efficient, well-designed clinical studies of drugs, devices, and biological products. Recent advances in science and technology, as well as innovative approaches…
Importance Accessing forcibly displaced, pediatric populations for vaccination is challenging, and precise vaccination rates remain largely unknown. Objective To estimate vaccination coverage and identify factors associated with vaccination in forcibly displaced, pediatric populations. Data Sources Six databases were searched in November 2023—Ovid MEDLINE,…
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