Mitigating the Burden of Medication Costs
This essay discusses medication cost-lowering strategies that clinicians can use in routine clinical and inpatient care to assist patients in affording and adhering to expensive therapy regimens.
JAMA Internal Medicine
Message From an Automated External Defibrillator
This case report describes a man in his 80s who received shock from an automated external defibrillator that registered 3 types of tachycardia.
Approach to Obesity Treatment in Primary Care – A Review
Importance More than 40% of US adults have obesity, which increases the risks for multiple chronic diseases and premature mortality. Historically, nonsurgical interventions often have not led to sufficient weight loss and maintenance to improve health, but highly effective antiobesity medications…
Unusual Tachycardia in a Patient With Chest Pain and Bradycardia
This case report describes a patient in their 50s who presented with squeezing chest pain for 4 hours and an initial electrocardiogram showing acute inferior wall and right ventricular infarction with third-degree atrioventricular block.
Possible Digoxin-Related Toxic Effects in a Patient
This case report describes a patient in their 70s with hypertension and heart failure presenting to the emergency department with chest discomfort, nausea, anorexia, and weakness.
Unraveling Wavy ST Segments – An Unusual Case of Syncope
This case report describes a patient in their 60s with gastroesophageal reflex disease who presented to the emergency department after loss of consciousness during dinner and daily intermittent chest discomfort.
Weakness and Syncope After Prolonged Diarrhea
This case report presents the electrocardiogram findings of a patient in their 70s history of hypertension, chronic kidney failure, and prolonged diarrhea who presented for repeated episodes of weakness and syncope.
Assessing the Clinical Utility of Liquid Biopsies Across 5 Potential Indications From Therapy Selection to Population Screening – A Review
Importance There has been great enthusiasm for the emerging technology of molecular-based tests to detect and quantify tumor DNA circulating in the bloodstream, colloquially known as a liquid biopsy. However, less attention has been given to how their clinical utility depends…
Testing Whether Cancer Screening Saves Lives – Implications for Randomized Clinical Trials of Multicancer Screening
Importance Cancer screening is often promoted as a means to save lives. The question of whether cancer screening truly saves lives is becoming increasingly relevant given the growing enthusiasm for multicancer detection blood tests (ie, liquid biopsies). It is possible in…
A Case of S1Q3T3A Classic Nonspecific Electrocardiogram Finding
This case report describes a patient in their 40s with a history of end-stage kidney disease secondary to hypertension and diabetes who presented with fatigue, cough, weakness, and dyspnea on exertion and was subsequently diagnosed with acute disseminated cryptococcal infection.
