A Distinctive Pattern With Coexisting Malignant Arrhythmias
This case report describes a patient in their 50s with spontaneous chest tightness and palpitations.
JAMA Internal Medicine
Azelastine Nasal Spray for Prevention of SARS-CoV-2 Infections – A Phase 2 Randomized Clinical Trial
Importance Limited pharmaceutical options exist for preexposure prophylaxis of COVID-19 beyond vaccination. Azelastine, an antihistamine nasal spray used for decades to treat allergic rhinitis, has in vitro antiviral activity against respiratory viruses, including SARS-CoV-2. Objective To determine the efficacy and safety of…
Higher-Valent Pneumococcal Conjugate Vaccines—Perspective for 2026
This Clinical Insights describes updated pneumococcal conjugate vaccines and their recommended use in adults.
The Harms of Inappropriate Food-Specific Immunoglobulin E TestingóLess Is More
This Teachable Moment describes a 56-year-old woman with a concern for a food allergy and bilateral leg muscle spasms.
Supporting Shared Decision-Making in Life-Altering Kidney Therapy Decisions for Older Adults – A Review
Importance Older adults represent the fastest-growing population initiating dialysis in the US. For older adults with advanced chronic kidney disease (CKD), initiating dialysis is often the default option presented, as they are often ineligible for kidney transplant. This approach may not…
An Uncommon Cause of Bradycardia Treated With Catheter Ablation
This case report describes a woman in her 50s who presented for evaluation of fatigue and exertional dyspnea.
Active Comparator New User Cohort Studies and Matching
This Guide to Statistics and Methods provides an overview of the active comparator, new user design and the use of propensity score matching.
Implementing Benzodiazepine Deprescribing in the Primary Care Clinic
This Clinical Insight contextualizes benzodiazepine deprescribing guidelines for primary care physicians and high-risk populations.
Sexual Health in Cancer Care—A Gap in Understanding
This Teachable Moment describes the need to identify individualized preferences, including sexual health, and mitigate assumptions to avoid unintentional harm done to patients during care.
An Unexpected Cause of Hypotension
This Teachable Moment discusses a case of hypotension caused by severe adrenal insufficiency in a man in his 70s.
