JAMA Dermatology

Mal de Meleda

This case report describes diffuse waxy palmoplantar hyperkeratosis in a symmetrically well-demarcated “gloves and socks” distribution with nail dystrophy.

Favre-Racouchot Syndrome

This case report describes multiple solitary open black comedones located bilaterally on the malar cheeks and temples as well as yellowish, smooth-surfaced papulonodular lesions in close association with the comedones.

Erythrasma

This case report describes well-demarcated brown plaques with overlying fine scale in the bilateral axillae, inframammary folds, and inguinal folds and widespread coral-red fluorescence.

Segmental Skin Induration in a Boy

An 11-year-old boy presented with progressive unilateral skin hardening on his right thigh and buttock for 7 years. What is your diagnosis?  

Tzanck Smear of Ulcerated Plaques

A man in his 30s with AIDS presented with acute onset painful scattered umbilicated papulopustules and ovoid ulcerated plaques with elevated, pink borders on the face, trunk, and extremities. What is your diagnosis.

A Pinpoint Orifice on the Glans Penis of a Young Man

A man in his 30s presents with a 14-year history of purulent penile discharge that has not responded to antibiotics or corticosteroids. A pinpoint orifice is found on the glans penis. What is your diagnosis?