JAMA Cardiology

Chest Pain and Chest Wall Deformity

A man in his mid-30s with a history of Crohn disease presented with several years of intermittent, nonexertional chest pressure. What would you do next?

Approach to the Postmarket Evaluation of Consumer Wearable Technologies

Importance  Consumer wearable technologies have wide applications, including some that have US Food and Drug Administration clearance for health-related notifications. While wearable technologies may have premarket testing, validation, and safety evaluation as part of a regulatory authorization process, information on their…

Asymptomatic Grade 6 Diastolic Murmur in an Adult

A previously healthy 55-year-old man presented to his local family medicine clinic after waking up with a buzzing sensation in his chest. What would you do next?

Left Ventricular Noncompaction Cardiomyopathy

This case report describes an echocardiography-based diagnosis of left ventricular noncompaction cardiomyopathy in a male patient in his 40s who presented with sudden-onset dyspnea.

Patent Foramen Ovale and Dysarthria in a Man in His 60s

This case report describes a diagnosis of patent foramen ovale in a man in his 60s presenting with stroke symptoms and multifocal infarcts on magnetic resonance imaging of the brain.

Preserving and Promoting Clinical Trial Representativeness – A Review of Existing Strategies and the Path Forward

Importance  Despite major advancements in cardiovascular clinical research, underrepresentation in cardiovascular clinical trials persists, limiting generalizability, access to novel therapies, and equitable care. Observations  Policymakers, funding bodies, researchers, and professional societies have increasingly acknowledged the scientific importance of representation of the intended…