JAMA

Chronic Pruritus – A Review

Importance  Chronic pruritus, defined as itch experienced for 6 weeks or longer, affects approximately 22% of people in their lifetime. Approximately 1% of physician visits are for the chief concern of chronic pruritus. Chronic pruritus is associated with adverse outcomes, including…

Chronic Chagas Disease in the US

This JAMA Insights provides recommendations for Chagas disease screening, diagnosis, and management in the US

“Inoculation” to Resist Misinformation

This JAMA Insights in the Communicating Medicine series explores the concept of “prebunking,” a psychological inoculation technique that could help prevent the spread of misinformation.

Blood Testing for Phosphatidylethanol

A 36-year-old man with obesity and dyslipidemia presented with elevated liver enzymes following a liver transplant to treat acute-on-chronic liver failure due to alcohol-associated hepatitis. What would you do next?

Service Animals in Health Care Settings

This JAMA Insights article reviews Americans with Disabilities Act (ADA) rules for patients, visitors, and other members of the public bringing service animals into health care settings.

A 3-Year-Old With Gingival Hemorrhage and Musculoskeletal Pain

A 3-year-old had spontaneous gingival hemorrhage and bilateral limb weakness with inability to bear weight. He had no preceding oral trauma or recent infection, took no regular medications, and had no recent use of aspirin or nonsteroidal anti-inflammatory drugs; his…

Climate Change and Mental Health

This JAMA Insights discusses the adverse effects of climate change on mental health and proposes solutions to help mitigate those effects.

Survival Benefit Associated With Participation in Clinical Trials of Anticancer Drugs – A Systematic Review and Meta-Analysis

Importance  Many cancer clinical investigators view clinical trials as offering better care for patients than routine clinical care. However, definitive evidence of clinical benefit from trial participation (hereafter referred to as the participation effect) has yet to emerge. Objective  To conduct a systematic…

Krill Oil for Knee Osteoarthritis – A Randomized Clinical Trial

Importance  Knee osteoarthritis is disabling, with few effective treatments. Preliminary evidence suggested that krill oil supplementation improved knee pain, but effects on knee osteoarthritis remain unclear. Objective  To evaluate efficacy of krill oil supplementation, compared with placebo, on knee pain in people…

Federal Trade Commission Actions on Prescription Drugs, 2000-2022

Importance  The Federal Trade Commission’s (FTC) oversight role in the pharmaceutical market is critical to the health of patients and the health care system. This study characterized the FTC’s policy on the pharmaceutical market in recent decades, identifying the types of…