JAMA

Opportunistic Salpingectomy for Prevention of Tubo-Ovarian Carcinoma – The European Society of Gynaecological Oncology Consensus Statements

Importance  The fallopian tube epithelium has been demonstrated to be an important source of tubo-ovarian carcinoma. Therefore, removal of the fallopian tubes during unrelated pelvic or abdominal surgery (opportunistic salpingectomy) can potentially lower future ovarian cancer risk. Objectives  To assess current evidence…

Management of Severe Refractory Asthma

This JAMA Insights explores the management of severe refractory asthma, including medications, access to specialists, and managing environmental triggers.

Individualized Perioperative Blood Pressure Management in Patients Undergoing Major Abdominal Surgery – The IMPROVE-multi Randomized Clinical Trial

Importance  Intraoperative hypotension is associated with organ injury. However, it remains unknown if targeted blood pressure management during surgery can improve clinical outcomes. Objective  To evaluate whether individualized vs routine perioperative blood pressure management during major abdominal surgery improves clinical outcomes in…

Microplastics and Human Health

This JAMA Insights discusses rising detection of microplastics in human tissue and the importance of international cooperation to limit plastic pollution.

Painful Hand Swelling With Finger Contractures

A 56-year-old woman with no history of rheumatic disease or hand injury had swelling and tenderness of the bilateral wrists, metacarpophalangeal and proximal interphalangeal joints, nodular palmar tendon thickening, and flexion contractures of all fingers; results of serologic testing for…

Syphilis – A Review

Importance  Syphilis is an infectious disease caused by Treponema pallidum, a gram-negative, spirochete bacterium. Worldwide, an estimated 8 million adults aged 18 to 49 years acquired syphilis in 2022. From 2019 to 2023, US syphilis cases increased by 61% overall, with diagnoses…