Importance Postural orthostatic tachycardia syndrome (POTS) is a chronic autonomic disorder characterized by excessive orthostatic tachycardia and multisystem symptoms that affects an estimated 0.1% to 1% of the US population. POTS can substantially impair daily functioning and quality of life….
This JAMA Insights discusses cannabinoid hyperemesis syndrome, including pathophysiology, clinical presentation, and the epidemiology and risk factors.
Importance Respiratory syncytial virus (RSV) is a leading cause of acute respiratory tract infection and a contributor to morbidity and mortality. Objective To synthesize evidence from recent randomized clinical trials and observational studies reporting on the effectiveness and safety of…
This JAMA Insights discusses suggested language for clinicians to use when communicating with families about brain death evaluation and determination.
Importance Influenza continues to cause significant mortality and morbidity in the US. Seasonal influenza vaccines reduce the severity of disease and prevent hospitalizations and death, especially among individuals at high risk. Objective To identify and summarize the most recently published…
Importance SARS-CoV-2 remains a substantial cause of respiratory illness, morbidity, and mortality. Evidence to date has demonstrated that COVID-19 vaccines reduce the risk of severe disease, including hospitalization and death. Objective This systematic review identifies and summarizes newly published studies…
This JAMA Insights discusses the etiology, clinical presentation, diagnostic evaluation, and treatment of narcolepsy.
Importance Rheumatoid arthritis (RA) is a chronic autoimmune disease that causes inflammation and destruction of cartilage and adjacent bone and can lead to irreversible disability. Rheumatoid arthritis affects 0.53% of adults worldwide and 0.74% of US adults. Observations Rheumatoid arthritis…
This JAMA Insights discusses the medical use of psilocybin, particularly for depression treatment, including emerging potential indications, safety, and future use.
Importance The incidence of cognitive decline increases exponentially with age, presenting important implications for professionals in cognitively demanding fields such as medicine. Despite an aging health care workforce, how jurisdictions assess for and address cognitive decline in physicians remains poorly…
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