Medical Knowledge

Amyotrophic Lateral Sclerosis – A Review

Importance  Amyotrophic lateral sclerosis (ALS) is a neurodegenerative disease characterized by progressive weakness due to degeneration of upper motor neurons in the brain and lower motor neurons in the brainstem and spinal cord. It affects approximately 25 000 individuals in the…

Promises, Pitfalls, and Paths Forward for the Pediatric Research Equity Act

Importance  Since its enactment in 2003, the Pediatric Research Equity Act (PREA) has significantly increased the number of pediatric drug studies performed and expanded pediatric drug labeling. Despite these advancements, many drugs used in children still lack pediatric-specific US Food…

Persistent Epiglottic Swelling With Ulceration

A male patient in his 60s with a foreign-body sensation in the throat was treated for acute epiglottitis, but supraglottic swelling persisted. What is your diagnosis?

Blunt Ocular Trauma in a 6-Year-Old Child

This case report describes the ocular injury incurred after blunt ocular trauma secondary to a fishhook in the left eye of a male child, aged 6 years.

Web-Based Amblyopia Decision Support Tool

Importance  Amblyopia is the leading cause of monocular decreased best-corrected vision in children. Early detection and intervention are key for optimal treatment outcomes; however, limited access to pediatric eye specialists may hinder timely care and affect visual outcomes. Given the…

Treatment of Anterior Cruciate Ligament Rupture

This JAMA Insights examines the efficacy of different management strategies for anterior cruciate ligament rupture, including surgical reconstruction and structured rehabilitation.

Parvovirus B19 Infection

This case report describes a previously healthy man in his 40s who presented with a 2-day history of asymptomatic rash, prior to which he experienced fever.

Navigating Practice Overview (Part 2)

Non-clinical aspects of an organization play critical roles in the success of health care practices. In this course, learners will identify the performance metrics that contribute to the success of medical practices, recognize how each area of practice management contributes…

Navigating Practice Overview (Part 2)

Non-clinical aspects of an organization play critical roles in the success of health care practices. In this course, learners will identify the performance metrics that contribute to the success of medical practices, recognize how each area of practice management contributes…